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Antibody Responses and Clinical Outcomes in Adults Hospitalized With Severe Coronavirus Disease 2019 (COVID-19): A Post hoc Analysis of LOTUS China Trial.
Ren L, Fan G, Wu W, Guo L, Wang Y, Li X, Wang C, Gu X, Li C, Wang Y, Wang G, Zhou F, Liu Z, Ge Q, Zhang Y, Li H, Zhang L, Xu J, Wang C, Wang J, Cao B. Ren L, et al. Among authors: zhang l, zhang y. Clin Infect Dis. 2021 May 18;72(10):e545-e551. doi: 10.1093/cid/ciaa1247. Clin Infect Dis. 2021. PMID: 32840287 Free PMC article.
The Pathogenesis and Treatment of COVID-19: A System Review.
Ji YL, Wu Y, Qiu Z, Ming H, Zhang Y, Zhang AN, Leng Y, Xia ZY. Ji YL, et al. Among authors: zhang an, zhang y. Biomed Environ Sci. 2021 Jan 20;34(1):50-60. doi: 10.3967/bes2021.007. Biomed Environ Sci. 2021. PMID: 33531107 Free PMC article. No abstract available.
Bispecific antibodies targeting distinct regions of the spike protein potently neutralize SARS-CoV-2 variants of concern.
Cho H, Gonzales-Wartz KK, Huang D, Yuan M, Peterson M, Liang J, Beutler N, Torres JL, Cong Y, Postnikova E, Bangaru S, Talana CA, Shi W, Yang ES, Zhang Y, Leung K, Wang L, Peng L, Skinner J, Li S, Wu NC, Liu H, Dacon C, Moyer T, Cohen M, Zhao M, Lee FE, Weinberg RS, Douagi I, Gross R, Schmaljohn C, Pegu A, Mascola JR, Holbrook M, Nemazee D, Rogers TF, Ward AB, Wilson IA, Crompton PD, Tan J. Cho H, et al. Among authors: zhang y. Sci Transl Med. 2021 Oct 20;13(616):eabj5413. doi: 10.1126/scitranslmed.abj5413. Epub 2021 Oct 20. Sci Transl Med. 2021. PMID: 34519517 Free PMC article.
Discovery of potential small molecular SARS-CoV-2 entry blockers targeting the spike protein.
Wang L, Wu Y, Yao S, Ge H, Zhu Y, Chen K, Chen WZ, Zhang Y, Zhu W, Wang HY, Guo Y, Ma PX, Ren PX, Zhang XL, Li HQ, Ali MA, Xu WQ, Jiang HL, Zhang LK, Zhu LL, Ye Y, Shang WJ, Bai F. Wang L, et al. Among authors: zhang xl, zhang lk, zhang y. Acta Pharmacol Sin. 2022 Apr;43(4):788-796. doi: 10.1038/s41401-021-00735-z. Epub 2021 Aug 4. Acta Pharmacol Sin. 2022. PMID: 34349236 Free PMC article.
Broadly neutralizing antibodies target the coronavirus fusion peptide.
Dacon C, Tucker C, Peng L, Lee CD, Lin TH, Yuan M, Cong Y, Wang L, Purser L, Williams JK, Pyo CW, Kosik I, Hu Z, Zhao M, Mohan D, Cooper AJR, Peterson M, Skinner J, Dixit S, Kollins E, Huzella L, Perry D, Byrum R, Lembirik S, Drawbaugh D, Eaton B, Zhang Y, Yang ES, Chen M, Leung K, Weinberg RS, Pegu A, Geraghty DE, Davidson E, Douagi I, Moir S, Yewdell JW, Schmaljohn C, Crompton PD, Holbrook MR, Nemazee D, Mascola JR, Wilson IA, Tan J. Dacon C, et al. Among authors: zhang y. Science. 2022 Aug 12;377(6607):728-735. doi: 10.1126/science.abq3773. Epub 2022 Jul 12. Science. 2022. PMID: 35857439 Free PMC article.
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