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Structure of the RNA-dependent RNA polymerase from COVID-19 virus.
Gao Y, Yan L, Huang Y, Liu F, Zhao Y, Cao L, Wang T, Sun Q, Ming Z, Zhang L, Ge J, Zheng L, Zhang Y, Wang H, Zhu Y, Zhu C, Hu T, Hua T, Zhang B, Yang X, Li J, Yang H, Liu Z, Xu W, Guddat LW, Wang Q, Lou Z, Rao Z. Gao Y, et al. Among authors: zhu c, zhu y. Science. 2020 May 15;368(6492):779-782. doi: 10.1126/science.abb7498. Epub 2020 Apr 10. Science. 2020. PMID: 32277040 Free PMC article.
Structures of cell wall arabinosyltransferases with the anti-tuberculosis drug ethambutol.
Zhang L, Zhao Y, Gao Y, Wu L, Gao R, Zhang Q, Wang Y, Wu C, Wu F, Gurcha SS, Veerapen N, Batt SM, Zhao W, Qin L, Yang X, Wang M, Zhu Y, Zhang B, Bi L, Zhang X, Yang H, Guddat LW, Xu W, Wang Q, Li J, Besra GS, Rao Z. Zhang L, et al. Among authors: zhu y. Science. 2020 Jun 12;368(6496):1211-1219. doi: 10.1126/science.aba9102. Epub 2020 Apr 23. Science. 2020. PMID: 32327601
Structural Basis for RNA Replication by the SARS-CoV-2 Polymerase.
Wang Q, Wu J, Wang H, Gao Y, Liu Q, Mu A, Ji W, Yan L, Zhu Y, Zhu C, Fang X, Yang X, Huang Y, Gao H, Liu F, Ge J, Sun Q, Yang X, Xu W, Liu Z, Yang H, Lou Z, Jiang B, Guddat LW, Gong P, Rao Z. Wang Q, et al. Among authors: zhu c, zhu y. Cell. 2020 Jul 23;182(2):417-428.e13. doi: 10.1016/j.cell.2020.05.034. Epub 2020 May 22. Cell. 2020. PMID: 32526208 Free PMC article.
Crystal structure of SARS-CoV-2 main protease in complex with protease inhibitor PF-07321332.
Zhao Y, Fang C, Zhang Q, Zhang R, Zhao X, Duan Y, Wang H, Zhu Y, Feng L, Zhao J, Shao M, Yang X, Zhang L, Peng C, Yang K, Ma D, Rao Z, Yang H. Zhao Y, et al. Among authors: zhu y. Protein Cell. 2022 Sep;13(9):689-693. doi: 10.1007/s13238-021-00883-2. Epub 2021 Oct 22. Protein Cell. 2022. PMID: 34687004 Free PMC article. No abstract available.
Structural basis for replicase polyprotein cleavage and substrate specificity of main protease from SARS-CoV-2.
Zhao Y, Zhu Y, Liu X, Jin Z, Duan Y, Zhang Q, Wu C, Feng L, Du X, Zhao J, Shao M, Zhang B, Yang X, Wu L, Ji X, Guddat LW, Yang K, Rao Z, Yang H. Zhao Y, et al. Among authors: zhu y. Proc Natl Acad Sci U S A. 2022 Apr 19;119(16):e2117142119. doi: 10.1073/pnas.2117142119. Epub 2022 Apr 5. Proc Natl Acad Sci U S A. 2022. PMID: 35380892 Free PMC article.
Structure-based design of pan-coronavirus inhibitors targeting host cathepsin L and calpain-1.
Xie X, Lan Q, Zhao J, Zhang S, Liu L, Zhang Y, Xu W, Shao M, Peng J, Xia S, Zhu Y, Zhang K, Zhang X, Zhang R, Li J, Dai W, Ge Z, Hu S, Yu C, Wang J, Ma D, Zheng M, Yang H, Xiao G, Rao Z, Lu L, Zhang L, Bai F, Zhao Y, Jiang S, Liu H. Xie X, et al. Among authors: zhu y. Signal Transduct Target Ther. 2024 Mar 6;9(1):54. doi: 10.1038/s41392-024-01758-8. Signal Transduct Target Ther. 2024. PMID: 38443334 Free PMC article.
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