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Highly accurate protein structure prediction for the human proteome.
Tunyasuvunakool K, Adler J, Wu Z, Green T, Zielinski M, Žídek A, Bridgland A, Cowie A, Meyer C, Laydon A, Velankar S, Kleywegt GJ, Bateman A, Evans R, Pritzel A, Figurnov M, Ronneberger O, Bates R, Kohl SAA, Potapenko A, Ballard AJ, Romera-Paredes B, Nikolov S, Jain R, Clancy E, Reiman D, Petersen S, Senior AW, Kavukcuoglu K, Birney E, Kohli P, Jumper J, Hassabis D. Tunyasuvunakool K, et al. Among authors: zielinski m. Nature. 2021 Aug;596(7873):590-596. doi: 10.1038/s41586-021-03828-1. Epub 2021 Jul 22. Nature. 2021. PMID: 34293799 Free PMC article.
Highly accurate protein structure prediction with AlphaFold.
Jumper J, Evans R, Pritzel A, Green T, Figurnov M, Ronneberger O, Tunyasuvunakool K, Bates R, Žídek A, Potapenko A, Bridgland A, Meyer C, Kohl SAA, Ballard AJ, Cowie A, Romera-Paredes B, Nikolov S, Jain R, Adler J, Back T, Petersen S, Reiman D, Clancy E, Zielinski M, Steinegger M, Pacholska M, Berghammer T, Bodenstein S, Silver D, Vinyals O, Senior AW, Kavukcuoglu K, Kohli P, Hassabis D. Jumper J, et al. Among authors: zielinski m. Nature. 2021 Aug;596(7873):583-589. doi: 10.1038/s41586-021-03819-2. Epub 2021 Jul 15. Nature. 2021. PMID: 34265844 Free PMC article.
Applying and improving AlphaFold at CASP14.
Jumper J, Evans R, Pritzel A, Green T, Figurnov M, Ronneberger O, Tunyasuvunakool K, Bates R, Žídek A, Potapenko A, Bridgland A, Meyer C, Kohl SAA, Ballard AJ, Cowie A, Romera-Paredes B, Nikolov S, Jain R, Adler J, Back T, Petersen S, Reiman D, Clancy E, Zielinski M, Steinegger M, Pacholska M, Berghammer T, Silver D, Vinyals O, Senior AW, Kavukcuoglu K, Kohli P, Hassabis D. Jumper J, et al. Among authors: zielinski m. Proteins. 2021 Dec;89(12):1711-1721. doi: 10.1002/prot.26257. Proteins. 2021. PMID: 34599769 Free PMC article.
A clinically applicable approach to continuous prediction of future acute kidney injury.
Tomašev N, Glorot X, Rae JW, Zielinski M, Askham H, Saraiva A, Mottram A, Meyer C, Ravuri S, Protsyuk I, Connell A, Hughes CO, Karthikesalingam A, Cornebise J, Montgomery H, Rees G, Laing C, Baker CR, Peterson K, Reeves R, Hassabis D, King D, Suleyman M, Back T, Nielson C, Ledsam JR, Mohamed S. Tomašev N, et al. Among authors: zielinski m. Nature. 2019 Aug;572(7767):116-119. doi: 10.1038/s41586-019-1390-1. Epub 2019 Jul 31. Nature. 2019. PMID: 31367026 Free PMC article.
Use of deep learning to develop continuous-risk models for adverse event prediction from electronic health records.
Tomašev N, Harris N, Baur S, Mottram A, Glorot X, Rae JW, Zielinski M, Askham H, Saraiva A, Magliulo V, Meyer C, Ravuri S, Protsyuk I, Connell A, Hughes CO, Karthikesalingam A, Cornebise J, Montgomery H, Rees G, Laing C, Baker CR, Osborne TF, Reeves R, Hassabis D, King D, Suleyman M, Back T, Nielson C, Seneviratne MG, Ledsam JR, Mohamed S. Tomašev N, et al. Among authors: zielinski m. Nat Protoc. 2021 Jun;16(6):2765-2787. doi: 10.1038/s41596-021-00513-5. Epub 2021 May 5. Nat Protoc. 2021. PMID: 33953393
Look and Outlook on Enzyme-Mediated Macrolide Resistance.
Golkar T, Zieliński M, Berghuis AM. Golkar T, et al. Among authors: zielinski m. Front Microbiol. 2018 Aug 20;9:1942. doi: 10.3389/fmicb.2018.01942. eCollection 2018. Front Microbiol. 2018. PMID: 30177927 Free PMC article. Review.
Probing the molecular and structural elements of ligands binding to the active site versus an allosteric pocket of the human farnesyl pyrophosphate synthase.
Gritzalis D, Park J, Chiu W, Cho H, Lin YS, De Schutter JW, Lacbay CM, Zielinski M, Berghuis AM, Tsantrizos YS. Gritzalis D, et al. Among authors: zielinski m. Bioorg Med Chem Lett. 2015 Mar 1;25(5):1117-23. doi: 10.1016/j.bmcl.2014.12.089. Epub 2015 Jan 13. Bioorg Med Chem Lett. 2015. PMID: 25630225
1,075 results