Zom GG - Search Results

1

TLR2 ligand-synthetic long peptide conjugates effectively stimulate tumor-draining lymph node T cells of cervical cancer patients.

Zom GG, Welters MJ, Loof NM, Goedemans R, Lougheed S, Valentijn RR, Zandvliet ML, Meeuwenoord NJ, Melief CJ, de Gruijl TD, Van der Marel GA, Filippov DV, Ossendorp F, Van der Burg SH. Zom GG, et al. Oncotarget. 2016 Oct 11;7(41):67087-67100. doi: 10.18632/oncotarget.11512. Oncotarget. 2016. PMID: 27564262 Free PMC article.

2

Efficient induction of antitumor immunity by synthetic toll-like receptor ligand-peptide conjugates.

Zom GG, Khan S, Britten CM, Sommandas V, Camps MG, Loof NM, Budden CF, Meeuwenoord NJ, Filippov DV, van der Marel GA, Overkleeft HS, Melief CJ, Ossendorp F. Zom GG, et al. Cancer Immunol Res. 2014 Aug;2(8):756-64. doi: 10.1158/2326-6066.CIR-13-0223. Epub 2014 Apr 21. Cancer Immunol Res. 2014. PMID: 24950688

3

Novel TLR2-binding adjuvant induces enhanced T cell responses and tumor eradication.

Zom GG, Willems MMJHP, Khan S, van der Sluis TC, Kleinovink JW, Camps MGM, van der Marel GA, Filippov DV, Melief CJM, Ossendorp F. Zom GG, et al. J Immunother Cancer. 2018 Dec 12;6(1):146. doi: 10.1186/s40425-018-0455-2. J Immunother Cancer. 2018. PMID: 30541631 Free PMC article.

4

Dual Synthetic Peptide Conjugate Vaccine Simultaneously Triggers TLR2 and NOD2 and Activates Human Dendritic Cells.

Zom GG, Willems MMJHP, Meeuwenoord NJ, Reintjens NRM, Tondini E, Khan S, Overkleeft HS, van der Marel GA, Codee JDC, Ossendorp F, Filippov DV. Zom GG, et al. Bioconjug Chem. 2019 Apr 17;30(4):1150-1161. doi: 10.1021/acs.bioconjchem.9b00087. Epub 2019 Mar 26. Bioconjug Chem. 2019. PMID: 30865430

5

Intradermal vaccination of HPV-16 E6 synthetic peptides conjugated to an optimized Toll-like receptor 2 ligand shows safety and potent T cell immunogenicity in patients with HPV-16 positive (pre-)malignant lesions.

Speetjens FM, Welters MJP, Slingerland M, van Poelgeest MIE, de Vos van Steenwijk PJ, Roozen I, Boekestijn S, Loof NM, Zom GG, Valentijn ARPM, Krebber WJ, Meeuwenoord NJ, Janssen CAH, Melief CJM, van der Marel GA, Filippov DV, van der Burg SH, Gelderblom H, Ossendorp F. Speetjens FM, et al. Among authors: zom gg. J Immunother Cancer. 2022 Oct;10(10):e005016. doi: 10.1136/jitc-2022-005016. J Immunother Cancer. 2022. PMID: 36261215 Free PMC article. Clinical Trial.

6

TLR ligand-peptide conjugate vaccines: toward clinical application.

Zom GG, Khan S, Filippov DV, Ossendorp F. Zom GG, et al. Adv Immunol. 2012;114:177-201. doi: 10.1016/B978-0-12-396548-6.00007-X. Adv Immunol. 2012. PMID: 22449782 Review.

7

Design, automated synthesis and immunological evaluation of NOD2-ligand-antigen conjugates.

Willems MM, Zom GG, Meeuwenoord N, Ossendorp FA, Overkleeft HS, van der Marel GA, Codée JD, Filippov DV. Willems MM, et al. Among authors: zom gg. Beilstein J Org Chem. 2014 Jun 26;10:1445-53. doi: 10.3762/bjoc.10.148. eCollection 2014. Beilstein J Org Chem. 2014. PMID: 24991299 Free PMC article.

8

N-tetradecylcarbamyl lipopeptides as novel agonists for Toll-like receptor 2.

Willems MM, Zom GG, Khan S, Meeuwenoord N, Melief CJ, van der Stelt M, Overkleeft HS, Codée JD, van der Marel GA, Ossendorp F, Filippov DV. Willems MM, et al. Among authors: zom gg. J Med Chem. 2014 Aug 14;57(15):6873-8. doi: 10.1021/jm500722p. Epub 2014 Jul 23. J Med Chem. 2014. PMID: 25019313

9

Two in one: improving synthetic long peptide vaccines by combining antigen and adjuvant in one molecule.

Zom GG, Filippov DV, van der Marel GA, Overkleeft HS, Melief CJ, Ossendorp F. Zom GG, et al. Oncoimmunology. 2014 Jul 3;3(7):e947892. doi: 10.4161/21624011.2014.947892. eCollection 2014. Oncoimmunology. 2014. PMID: 25610736 Free PMC article.

10

Lipophilic Muramyl Dipeptide-Antigen Conjugates as Immunostimulating Agents.

Willems MM, Zom GG, Meeuwenoord N, Khan S, Ossendorp F, Overkleeft HS, van der Marel GA, Filippov DV, Codée JD. Willems MM, et al. Among authors: zom gg. ChemMedChem. 2016 Jan 19;11(2):190-8. doi: 10.1002/cmdc.201500196. Epub 2015 Jun 9. ChemMedChem. 2016. PMID: 26059481

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