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A single dose of self-transcribing and replicating RNA-based SARS-CoV-2 vaccine produces protective adaptive immunity in mice.
de Alwis R, Gan ES, Chen S, Leong YS, Tan HC, Zhang SL, Yau C, Low JGH, Kalimuddin S, Matsuda D, Allen EC, Hartman P, Park KJ, Alayyoubi M, Bhaskaran H, Dukanovic A, Bao Y, Clemente B, Vega J, Roberts S, Gonzalez JA, Sablad M, Yelin R, Taylor W, Tachikawa K, Parker S, Karmali P, Davis J, Sullivan BM, Sullivan SM, Hughes SG, Chivukula P, Ooi EE. de Alwis R, et al. Mol Ther. 2021 Jun 2;29(6):1970-1983. doi: 10.1016/j.ymthe.2021.04.001. Epub 2021 Apr 5. Mol Ther. 2021. PMID: 33823303 Free PMC article.
Antibody sugars are bittersweet.
de Alwis R, Ooi EE. de Alwis R, et al. Science. 2021 Jun 4;372(6546):1041-1042. doi: 10.1126/science.abj0435. Science. 2021. PMID: 34083476 No abstract available.
52 results