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Deletion of leucine 61 in glucose-6-phosphate dehydrogenase leads to chronic nonspherocytic anemia, granulocyte dysfunction, and increased susceptibility to infections.
van Bruggen R, Bautista JM, Petropoulou T, de Boer M, van Zwieten R, Gómez-Gallego F, Belohradsky BH, Hartwig NG, Stevens D, Mason PJ, Roos D. van Bruggen R, et al. Among authors: van zwieten r. Blood. 2002 Aug 1;100(3):1026-30. doi: 10.1182/blood.v100.3.1026. Blood. 2002. PMID: 12130518 Free article.
Humanized MISTRG as a preclinical in vivo model to study human neutrophil-mediated immune processes.
Martinez-Sanz P, Laurent ARG, Slot E, Hoogenboezem M, Bąbała N, van Bruggen R, Rongvaux A, Flavell RA, Tytgat GAM, Franke K, Matlung HL, Kuijpers TW, Amsen D, Karrich JJ. Martinez-Sanz P, et al. Among authors: van bruggen r. Front Immunol. 2023 Mar 8;14:1105103. doi: 10.3389/fimmu.2023.1105103. eCollection 2023. Front Immunol. 2023. PMID: 36969261 Free PMC article.
Increased retention of functional mitochondria in mature sickle red blood cells is associated with increased sickling tendency, hemolysis and oxidative stress.
Esperti S, Nader E, Stier A, Boisson C, Carin R, Marano M, Robert M, Martin M, Horand F, Cibiel A, Renoux C, Van Bruggen R, Blans C, Dargaud Y, Joly P, Gauthier A, Poutrel S, Romana M, Roussel D, Connes P. Esperti S, et al. Among authors: van bruggen r. Haematologica. 2023 Nov 1;108(11):3086-3094. doi: 10.3324/haematol.2023.282684. Haematologica. 2023. PMID: 37259576 Free PMC article.
Biotinylated Platelets: A Promising Labeling Technique?
van Wonderen SF, van Baarle FLF, de Bruin S, Peters AL, de Korte D, van Bruggen R, Vlaar APJ. van Wonderen SF, et al. Among authors: van bruggen r, van baarle flf. Transfus Med Rev. 2023 Apr;37(2):150719. doi: 10.1016/j.tmrv.2023.01.001. Epub 2023 Jan 13. Transfus Med Rev. 2023. PMID: 36697309 Free article. Review.
Oxidative killing of microbes by neutrophils.
Roos D, van Bruggen R, Meischl C. Roos D, et al. Among authors: van bruggen r. Microbes Infect. 2003 Nov;5(14):1307-15. doi: 10.1016/j.micinf.2003.09.009. Microbes Infect. 2003. PMID: 14613774 Free article. Review.
Single-cell optical imaging of the phagocyte NADPH oxidase.
van Manen HJ, van Bruggen R, Roos D, Otto C. van Manen HJ, et al. Among authors: van bruggen r. Antioxid Redox Signal. 2006 Sep-Oct;8(9-10):1509-22. doi: 10.1089/ars.2006.8.1509. Antioxid Redox Signal. 2006. PMID: 16987007
162 results