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Hepatic low-density lipoprotein receptor-related protein deficiency in mice increases atherosclerosis independent of plasma cholesterol.
Espirito Santo SM, Pires NM, Boesten LS, Gerritsen G, Bovenschen N, van Dijk KW, Jukema JW, Princen HM, Bensadoun A, Li WP, Herz J, Havekes LM, van Vlijmen BJ. Espirito Santo SM, et al. Among authors: van vlijmen bj, van dijk kw. Blood. 2004 May 15;103(10):3777-82. doi: 10.1182/blood-2003-11-4051. Epub 2004 Jan 22. Blood. 2004. PMID: 14739216 Free article.
Apolipoprotein CI causes hypertriglyceridemia independent of the very-low-density lipoprotein receptor and apolipoprotein CIII in mice.
van der Hoogt CC, Berbée JF, Espirito Santo SM, Gerritsen G, Krom YD, van der Zee A, Havekes LM, van Dijk KW, Rensen PC. van der Hoogt CC, et al. Among authors: van dijk kw, van der zee a. Biochim Biophys Acta. 2006 Feb;1761(2):213-20. doi: 10.1016/j.bbalip.2006.01.002. Epub 2006 Jan 27. Biochim Biophys Acta. 2006. PMID: 16478678
The hepatic uptake of VLDL in lrp-ldlr-/-vldlr-/- mice is regulated by LPL activity and involves proteoglycans and SR-BI.
Hu L, van der Hoogt CC, Espirito Santo SM, Out R, Kypreos KE, van Vlijmen BJ, Van Berkel TJ, Romijn JA, Havekes LM, van Dijk KW, Rensen PC. Hu L, et al. Among authors: van vlijmen bj, van der hoogt cc, van dijk kw, van berkel tj. J Lipid Res. 2008 Jul;49(7):1553-61. doi: 10.1194/jlr.M800130-JLR200. Epub 2008 Mar 26. J Lipid Res. 2008. PMID: 18367731 Free article.
In the absence of the low density lipoprotein receptor, human apolipoprotein C1 overexpression in transgenic mice inhibits the hepatic uptake of very low density lipoproteins via a receptor-associated protein-sensitive pathway.
Jong MC, Dahlmans VE, van Gorp PJ, van Dijk KW, Breuer ML, Hofker MH, Havekes LM. Jong MC, et al. Among authors: van gorp pj, van dijk kw. J Clin Invest. 1996 Nov 15;98(10):2259-67. doi: 10.1172/JCI119036. J Clin Invest. 1996. PMID: 8941642 Free PMC article.
Reversal of hypercholesterolemia in apolipoprotein E2 and apolipoprotein E3-Leiden transgenic mice by adenovirus-mediated gene transfer of the VLDL receptor.
van Dijk KW, van Vlijmen BJ, van der Zee A, van't Hof B, van der Boom H, Kobayashi K, Chan L, Havekes LM, Hofker MH. van Dijk KW, et al. Among authors: van vlijmen bj, van der boom h, van der zee a, van t hof b. Arterioscler Thromb Vasc Biol. 1998 Jan;18(1):7-12. doi: 10.1161/01.atv.18.1.7. Arterioscler Thromb Vasc Biol. 1998. PMID: 9445249
Reversal of hyperlipidaemia in apolipoprotein C1 transgenic mice by adenovirus-mediated gene delivery of the low-density-lipoprotein receptor, but not by the very-low-density-lipoprotein receptor.
Jong MC, van Dijk KW, Dahlmans VE, Van der Boom H, Kobayashi K, Oka K, Siest G, Chan L, Hofker MH, Havekes LM. Jong MC, et al. Among authors: van dijk kw, van der boom h. Biochem J. 1999 Mar 1;338 ( Pt 2)(Pt 2):281-7. Biochem J. 1999. PMID: 10024503 Free PMC article.
Hyperlipidemia of ApoE2(Arg(158)-Cys) and ApoE3-Leiden transgenic mice is modulated predominantly by LDL receptor expression.
van Dijk KW, van Vlijmen BJ, de Winther MP, van 't Hof B, van der Zee A, van der Boom H, Havekes LM, Hofker MH. van Dijk KW, et al. Among authors: van vlijmen bj, van der boom h, van der zee a, van t hof b. Arterioscler Thromb Vasc Biol. 1999 Dec;19(12):2945-51. doi: 10.1161/01.atv.19.12.2945. Arterioscler Thromb Vasc Biol. 1999. PMID: 10591674
199 results