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T-cell stimulating vaccines empower CD3 bispecific antibody therapy in solid tumors.
Middelburg J, Sluijter M, Schaap G, Göynük B, Lloyd K, Ovcinnikovs V, Zom GG, Marijnissen RJ, Groeneveldt C, Griffioen L, Sandker GGW, Heskamp S, van der Burg SH, Arakelian T, Ossendorp F, Arens R, Schuurman J, Kemper K, van Hall T. Middelburg J, et al. Among authors: van hall t. Nat Commun. 2024 Jan 2;15(1):48. doi: 10.1038/s41467-023-44308-6. Nat Commun. 2024. PMID: 38167722 Free PMC article.
PD-L1 checkpoint blockade promotes regulatory T cell activity that underlies therapy resistance.
van Gulijk M, van Krimpen A, Schetters S, Eterman M, van Elsas M, Mankor J, Klaase L, de Bruijn M, van Nimwegen M, van Tienhoven T, van Ijcken W, Boon L, van der Schoot J, Verdoes M, Scheeren F, van der Burg SH, Lambrecht BN, Stadhouders R, Dammeijer F, Aerts J, van Hall T. van Gulijk M, et al. Among authors: van hall t. Sci Immunol. 2023 May 19;8(83):eabn6173. doi: 10.1126/sciimmunol.abn6173. Epub 2023 May 19. Sci Immunol. 2023. PMID: 37205768
Socs1-knockout in skin-resident CD4+ T cells in a protracted contact-allergic reaction results in an autonomous skin inflammation with features of early-stage mycosis fungoides.
Luo Y, Vermeer MH, de Haan S, Kinderman P, de Gruijl FR, van Hall T, Tensen CP. Luo Y, et al. Among authors: van hall t. Biochem Biophys Rep. 2023 Aug 22;35:101535. doi: 10.1016/j.bbrep.2023.101535. eCollection 2023 Sep. Biochem Biophys Rep. 2023. PMID: 37664523 Free PMC article.
In vivo modelling of cutaneous T-cell lymphoma: The role of SOCS1.
Luo Y, Vermeer MH, de Gruijl FR, Zoutman WH, Sluijter M, van Hall T, Tensen CP. Luo Y, et al. Among authors: van hall t. Front Oncol. 2022 Nov 24;12:1031052. doi: 10.3389/fonc.2022.1031052. eCollection 2022. Front Oncol. 2022. PMID: 36505769 Free PMC article.
Selective cytotoxic T-lymphocyte targeting of tumor immune escape variants.
van Hall T, Wolpert EZ, van Veelen P, Laban S, van der Veer M, Roseboom M, Bres S, Grufman P, de Ru A, Meiring H, de Jong A, Franken K, Teixeira A, Valentijn R, Drijfhout JW, Koning F, Camps M, Ossendorp F, Kärre K, Ljunggren HG, Melief CJ, Offringa R. van Hall T, et al. Among authors: van der veer m, van veelen p. Nat Med. 2006 Apr;12(4):417-24. doi: 10.1038/nm1381. Epub 2006 Mar 19. Nat Med. 2006. PMID: 16550190
121 results