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Pro-apoptotic protein Noxa regulates memory T cell population size and protects against lethal immunopathology.
Wensveen FM, Klarenbeek PL, van Gisbergen KP, Pascutti MF, Derks IA, van Schaik BD, Ten Brinke A, de Vries N, Cekinovic D, Jonjic S, van Lier RA, Eldering E. Wensveen FM, et al. Among authors: van lier ra, van gisbergen kp, van schaik bd. J Immunol. 2013 Feb 1;190(3):1180-91. doi: 10.4049/jimmunol.1202304. Epub 2012 Dec 31. J Immunol. 2013. PMID: 23277490
Human T-cell memory consists mainly of unexpanded clones.
Klarenbeek PL, Tak PP, van Schaik BD, Zwinderman AH, Jakobs ME, Zhang Z, van Kampen AH, van Lier RA, Baas F, de Vries N. Klarenbeek PL, et al. Among authors: van kampen ah, van lier ra, van schaik bd. Immunol Lett. 2010 Sep 6;133(1):42-8. doi: 10.1016/j.imlet.2010.06.011. Epub 2010 Jul 16. Immunol Lett. 2010. PMID: 20621124
Inflamed target tissue provides a specific niche for highly expanded T-cell clones in early human autoimmune disease.
Klarenbeek PL, de Hair MJ, Doorenspleet ME, van Schaik BD, Esveldt RE, van de Sande MG, Cantaert T, Gerlag DM, Baeten D, van Kampen AH, Baas F, Tak PP, de Vries N. Klarenbeek PL, et al. Among authors: van kampen ah, van de sande mg, van schaik bd. Ann Rheum Dis. 2012 Jun;71(6):1088-93. doi: 10.1136/annrheumdis-2011-200612. Epub 2012 Jan 31. Ann Rheum Dis. 2012. PMID: 22294635
Deep sequencing of antiviral T-cell responses to HCMV and EBV in humans reveals a stable repertoire that is maintained for many years.
Klarenbeek PL, Remmerswaal EB, ten Berge IJ, Doorenspleet ME, van Schaik BD, Esveldt RE, Koch SD, ten Brinke A, van Kampen AH, Bemelman FJ, Tak PP, Baas F, de Vries N, van Lier RA. Klarenbeek PL, et al. Among authors: van kampen ah, van lier ra, van schaik bd. PLoS Pathog. 2012 Sep;8(9):e1002889. doi: 10.1371/journal.ppat.1002889. Epub 2012 Sep 27. PLoS Pathog. 2012. PMID: 23028307 Free PMC article.
Clonal evolution of CD8+ T cell responses against latent viruses: relationship among phenotype, localization, and function.
Remmerswaal EB, Klarenbeek PL, Alves NL, Doorenspleet ME, van Schaik BD, Esveldt RE, Idu MM, van Leeuwen EM, van der Bom-Baylon N, van Kampen AH, Koch SD, Pircher H, Bemelman FJ, Ten Brinke A, Baas F, Ten Berge IJ, van Lier RA, de Vries N. Remmerswaal EB, et al. Among authors: van kampen ah, van lier ra, van leeuwen em, van schaik bd, van der bom baylon n. J Virol. 2015 Jan;89(1):568-80. doi: 10.1128/JVI.02003-14. Epub 2014 Oct 22. J Virol. 2015. PMID: 25339770 Free PMC article.
Somatic Variation of T-Cell Receptor Genes Strongly Associate with HLA Class Restriction.
Klarenbeek PL, Doorenspleet ME, Esveldt RE, van Schaik BD, Lardy N, van Kampen AH, Tak PP, Plenge RM, Baas F, de Bakker PI, de Vries N. Klarenbeek PL, et al. Among authors: van kampen ah, van schaik bd. PLoS One. 2015 Oct 30;10(10):e0140815. doi: 10.1371/journal.pone.0140815. eCollection 2015. PLoS One. 2015. PMID: 26517366 Free PMC article.
Computational Model Reveals Limited Correlation between Germinal Center B-Cell Subclone Abundancy and Affinity: Implications for Repertoire Sequencing.
Reshetova P, van Schaik BD, Klarenbeek PL, Doorenspleet ME, Esveldt RE, Tak PP, Guikema JE, de Vries N, van Kampen AH. Reshetova P, et al. Among authors: van kampen ah, van schaik bd. Front Immunol. 2017 Mar 6;8:221. doi: 10.3389/fimmu.2017.00221. eCollection 2017. Front Immunol. 2017. PMID: 28321219 Free PMC article.
57 results