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Low-density lipoproteins cause atherosclerotic cardiovascular disease. 1. Evidence from genetic, epidemiologic, and clinical studies. A consensus statement from the European Atherosclerosis Society Consensus Panel.
Ference BA, Ginsberg HN, Graham I, Ray KK, Packard CJ, Bruckert E, Hegele RA, Krauss RM, Raal FJ, Schunkert H, Watts GF, Borén J, Fazio S, Horton JD, Masana L, Nicholls SJ, Nordestgaard BG, van de Sluis B, Taskinen MR, Tokgözoglu L, Landmesser U, Laufs U, Wiklund O, Stock JK, Chapman MJ, Catapano AL. Ference BA, et al. Among authors: van de sluis b. Eur Heart J. 2017 Aug 21;38(32):2459-2472. doi: 10.1093/eurheartj/ehx144. Eur Heart J. 2017. PMID: 28444290 Free PMC article. Review.
The chemotherapeutic drug doxorubicin does not exacerbate p16Ink4a-positive senescent cell accumulation and cardiometabolic disease development in young adult female LDLR-deficient mice.
Postmus AC, Kruit JK, Eilers RE, Havinga R, Koster MH, Johmura Y, Nakanishi M, van de Sluis B, Jonker JW. Postmus AC, et al. Among authors: van de sluis b. Toxicol Appl Pharmacol. 2023 Jun 1;468:116531. doi: 10.1016/j.taap.2023.116531. Epub 2023 Apr 23. Toxicol Appl Pharmacol. 2023. PMID: 37088304 Free article.
A common variant in CCDC93 protects against myocardial infarction and cardiovascular mortality by regulating endosomal trafficking of low-density lipoprotein receptor.
Rimbert A, Dalila N, Wolters JC, Huijkman N, Smit M, Kloosterhuis N, Riemsma M, van der Veen Y, Singla A, van Dijk F; Biobank-Based Integrative Omics Studies Consortium; Frikke-Schmidt R, Burstein E, Tybjærg-Hansen A, van de Sluis B, Kuivenhoven JA. Rimbert A, et al. Among authors: van dijk f, van de sluis b, van der veen y. Eur Heart J. 2020 Mar 1;41(9):1040-1053. doi: 10.1093/eurheartj/ehz727. Eur Heart J. 2020. PMID: 31630160
Low-density lipoproteins cause atherosclerotic cardiovascular disease: pathophysiological, genetic, and therapeutic insights: a consensus statement from the European Atherosclerosis Society Consensus Panel.
Borén J, Chapman MJ, Krauss RM, Packard CJ, Bentzon JF, Binder CJ, Daemen MJ, Demer LL, Hegele RA, Nicholls SJ, Nordestgaard BG, Watts GF, Bruckert E, Fazio S, Ference BA, Graham I, Horton JD, Landmesser U, Laufs U, Masana L, Pasterkamp G, Raal FJ, Ray KK, Schunkert H, Taskinen MR, van de Sluis B, Wiklund O, Tokgozoglu L, Catapano AL, Ginsberg HN. Borén J, et al. Among authors: van de sluis b. Eur Heart J. 2020 Jun 21;41(24):2313-2330. doi: 10.1093/eurheartj/ehz962. Eur Heart J. 2020. PMID: 32052833 Free PMC article. No abstract available.
VLDL Biogenesis and Secretion: It Takes a Village.
van Zwol W, van de Sluis B, Ginsberg HN, Kuivenhoven JA. van Zwol W, et al. Among authors: van de sluis b. Circ Res. 2024 Jan 19;134(2):226-244. doi: 10.1161/CIRCRESAHA.123.323284. Epub 2024 Jan 18. Circ Res. 2024. PMID: 38236950 Review.
The NADPH oxidase Nox4 has anti-atherosclerotic functions.
Schürmann C, Rezende F, Kruse C, Yasar Y, Löwe O, Fork C, van de Sluis B, Bremer R, Weissmann N, Shah AM, Jo H, Brandes RP, Schröder K. Schürmann C, et al. Among authors: van de sluis b. Eur Heart J. 2015 Dec 21;36(48):3447-56. doi: 10.1093/eurheartj/ehv460. Epub 2015 Sep 17. Eur Heart J. 2015. PMID: 26385958 Free PMC article.
CCC- and WASH-mediated endosomal sorting of LDLR is required for normal clearance of circulating LDL.
Bartuzi P, Billadeau DD, Favier R, Rong S, Dekker D, Fedoseienko A, Fieten H, Wijers M, Levels JH, Huijkman N, Kloosterhuis N, van der Molen H, Brufau G, Groen AK, Elliott AM, Kuivenhoven JA, Plecko B, Grangl G, McGaughran J, Horton JD, Burstein E, Hofker MH, van de Sluis B. Bartuzi P, et al. Among authors: van der molen h, van de sluis b. Nat Commun. 2016 Mar 11;7:10961. doi: 10.1038/ncomms10961. Nat Commun. 2016. PMID: 26965651 Free PMC article.
Recycling the LDL receptor to combat atherosclerosis.
Vos D, Kuivenhoven JA, van de Sluis B. Vos D, et al. Among authors: van de sluis b. Aging (Albany NY). 2018 Nov 27;10(12):3638-3640. doi: 10.18632/aging.101681. Aging (Albany NY). 2018. PMID: 30482888 Free PMC article. No abstract available.
Variants in the GPR146 Gene Are Associated With a Favorable Cardiometabolic Risk Profile.
Rimbert A, Yeung MW, Dalila N, Thio CHL, Yu H, Loaiza N, Oldoni F, van der Graaf A, Wang S, Said MA, Blauw LL, Girardeau A, Bray L, Caillaud A, Bloks VW, Marrec M, Moulin P, Rensen PCN, van de Sluis B, Snieder H, Di Filippo M, van der Harst P, Tybjaerg-Hansen A, Zimmerman P, Cariou B, Kuivenhoven JA. Rimbert A, et al. Among authors: van der harst p, van der graaf a, van de sluis b. Arterioscler Thromb Vasc Biol. 2022 Oct;42(10):1262-1271. doi: 10.1161/ATVBAHA.122.317514. Epub 2022 Sep 1. Arterioscler Thromb Vasc Biol. 2022. PMID: 36047410 Free article.
106 results