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Page 1
A fluorescent broad-spectrum proteasome inhibitor for labeling proteasomes in vitro and in vivo.
Verdoes M, Florea BI, Menendez-Benito V, Maynard CJ, Witte MD, van der Linden WA, van den Nieuwendijk AM, Hofmann T, Berkers CR, van Leeuwen FW, Groothuis TA, Leeuwenburgh MA, Ovaa H, Neefjes JJ, Filippov DV, van der Marel GA, Dantuma NP, Overkleeft HS. Verdoes M, et al. Among authors: van der marel ga, van der linden wa, van den nieuwendijk am, van leeuwen fw. Chem Biol. 2006 Nov;13(11):1217-26. doi: 10.1016/j.chembiol.2006.09.013. Chem Biol. 2006. PMID: 17114003
Azido-BODIPY acid reveals quantitative Staudinger-Bertozzi ligation in two-step activity-based proteasome profiling.
Verdoes M, Florea BI, Hillaert U, Willems LI, van der Linden WA, Sae-Heng M, Filippov DV, Kisselev AF, van der Marel GA, Overkleeft HS. Verdoes M, et al. Among authors: van der marel ga, van der linden wa. Chembiochem. 2008 Jul 21;9(11):1735-8. doi: 10.1002/cbic.200800231. Chembiochem. 2008. PMID: 18600815 Free PMC article. No abstract available.
A panel of subunit-selective activity-based proteasome probes.
Verdoes M, Willems LI, van der Linden WA, Duivenvoorden BA, van der Marel GA, Florea BI, Kisselev AF, Overkleeft HS. Verdoes M, et al. Among authors: van der marel ga, van der linden wa. Org Biomol Chem. 2010 Jun 21;8(12):2719-27. doi: 10.1039/c001036g. Epub 2010 May 6. Org Biomol Chem. 2010. PMID: 20449511 Free PMC article.
Activity-based profiling reveals reactivity of the murine thymoproteasome-specific subunit beta5t.
Florea BI, Verdoes M, Li N, van der Linden WA, Geurink PP, van den Elst H, Hofmann T, de Ru A, van Veelen PA, Tanaka K, Sasaki K, Murata S, den Dulk H, Brouwer J, Ossendorp FA, Kisselev AF, Overkleeft HS. Florea BI, et al. Among authors: van den elst h, van der linden wa, van veelen pa. Chem Biol. 2010 Aug 27;17(8):795-801. doi: 10.1016/j.chembiol.2010.05.027. Chem Biol. 2010. PMID: 20797608 Free PMC article.
Discovery of a potent and highly β1 specific proteasome inhibitor from a focused library of urea-containing peptide vinyl sulfones and peptide epoxyketones.
van der Linden WA, Willems LI, Shabaneh TB, Li N, Ruben M, Florea BI, van der Marel GA, Kaiser M, Kisselev AF, Overkleeft HS. van der Linden WA, et al. Among authors: van der marel ga. Org Biomol Chem. 2012 Jan 7;10(1):181-94. doi: 10.1039/c1ob06554h. Epub 2011 Nov 22. Org Biomol Chem. 2012. PMID: 22105930 Free PMC article.
Nature of pharmacophore influences active site specificity of proteasome inhibitors.
Screen M, Britton M, Downey SL, Verdoes M, Voges MJ, Blom AE, Geurink PP, Risseeuw MD, Florea BI, van der Linden WA, Pletnev AA, Overkleeft HS, Kisselev AF. Screen M, et al. Among authors: van der linden wa. J Biol Chem. 2010 Dec 17;285(51):40125-34. doi: 10.1074/jbc.M110.160606. Epub 2010 Oct 11. J Biol Chem. 2010. PMID: 20937826 Free PMC article.
Bioorthogonal chemistry: applications in activity-based protein profiling.
Willems LI, van der Linden WA, Li N, Li KY, Liu N, Hoogendoorn S, van der Marel GA, Florea BI, Overkleeft HS. Willems LI, et al. Among authors: van der marel ga, van der linden wa. Acc Chem Res. 2011 Sep 20;44(9):718-29. doi: 10.1021/ar200125k. Epub 2011 Jul 28. Acc Chem Res. 2011. PMID: 21797256
32 results