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(R)-3,3,3-Trifluoro-2-hydroxy-2-methylpropionamides are orally active inhibitors of pyruvate dehydrogenase kinase.
J Med Chem. 1999 Jul 29;42(15):2741-6. doi: 10.1021/jm9902584.
J Med Chem. 1999.
PMID: 10425084
No abstract available.
Hypoglycemic prodrugs of 4-(2,2-dimethyl-1-oxopropyl)benzoic acid.
Aicher TD, Bebernitz GR, Bell PA, Brand LJ, Dain JG, Deems R, Fillers WS, Foley JE, Knorr DC, Nadelson J, Otero DA, Simpson R, Strohschein RJ, Young DA.
Aicher TD, et al. Among authors: knorr dc.
J Med Chem. 1999 Jan 14;42(1):153-63. doi: 10.1021/jm980438y.
J Med Chem. 1999.
PMID: 9888840
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Secondary amides of (R)-3,3,3-trifluoro-2-hydroxy-2-methylpropionic acid as inhibitors of pyruvate dehydrogenase kinase.
Aicher TD, Anderson RC, Gao J, Shetty SS, Coppola GM, Stanton JL, Knorr DC, Sperbeck DM, Brand LJ, Vinluan CC, Kaplan EL, Dragland CJ, Tomaselli HC, Islam A, Lozito RJ, Liu X, Maniara WM, Fillers WS, DelGrande D, Walter RE, Mann WR.
Aicher TD, et al. Among authors: knorr dc.
J Med Chem. 2000 Jan 27;43(2):236-49. doi: 10.1021/jm990358+.
J Med Chem. 2000.
PMID: 10649979
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Anilides of (R)-trifluoro-2-hydroxy-2-methylpropionic acid as inhibitors of pyruvate dehydrogenase kinase.
Bebernitz GR, Aicher TD, Stanton JL, Gao J, Shetty SS, Knorr DC, Strohschein RJ, Tan J, Brand LJ, Liu C, Wang WH, Vinluan CC, Kaplan EL, Dragland CJ, DelGrande D, Islam A, Lozito RJ, Liu X, Maniara WM, Mann WR.
Bebernitz GR, et al. Among authors: knorr dc.
J Med Chem. 2000 Jun 1;43(11):2248-57. doi: 10.1021/jm0000923.
J Med Chem. 2000.
PMID: 10841803
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Perhydroquinolylbenzamides as novel inhibitors of 11beta-hydroxysteroid dehydrogenase type 1.
Coppola GM, Kukkola PJ, Stanton JL, Neubert AD, Marcopulos N, Bilci NA, Wang H, Tomaselli HC, Tan J, Aicher TD, Knorr DC, Jeng AY, Dardik B, Chatelain RE.
Coppola GM, et al. Among authors: knorr dc.
J Med Chem. 2005 Oct 20;48(21):6696-712. doi: 10.1021/jm058228q.
J Med Chem. 2005.
PMID: 16220986
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Substituted tetrahydropyrrolo[2,1-b]oxazol-5(6H)-ones and tetrahydropyrrolo[2,1-b]thiazol-5(6H)-ones as hypoglycemic agents.
Aicher TD, Balkan B, Bell PA, Brand LJ, Cheon SH, Deems RO, Fell JB, Fillers WS, Fraser JD, Gao J, Knorr DC, Kahle GG, Leone CL, Nadelson J, Simpson R, Smith HC.
Aicher TD, et al. Among authors: knorr dc.
J Med Chem. 1998 Nov 5;41(23):4556-66. doi: 10.1021/jm9803121.
J Med Chem. 1998.
PMID: 9804695
Item in Clipboard
Novel tricyclic systems. Oxazole, thiazole, and imidazole analogs of the amitriptyline type.
Galantay EE, Simpson R, Corriveau G, Denzer M, Knorr DC, Strohschein RJ, Paolella NA, Uike Y.
Galantay EE, et al. Among authors: knorr dc.
J Med Chem. 1974 Dec;17(12):1316-27. doi: 10.1021/jm00258a018.
J Med Chem. 1974.
PMID: 4427328
No abstract available.
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