Schmalhofer WA - Search Results

1

Binding of correolide to K(v)1 family potassium channels. Mapping the domains of high affinity interaction.

Hanner M, Schmalhofer WA, Green B, Bordallo C, Liu J, Slaughter RS, Kaczorowski GJ, Garcia ML. Hanner M, et al. Among authors: schmalhofer wa. J Biol Chem. 1999 Sep 3;274(36):25237-44. doi: 10.1074/jbc.274.36.25237. J Biol Chem. 1999. PMID: 10464244 Free article.

2

Identification of a new class of inhibitors of the voltage-gated potassium channel, Kv1.3, with immunosuppressant properties.

Schmalhofer WA, Bao J, McManus OB, Green B, Matyskiela M, Wunderler D, Bugianesi RM, Felix JP, Hanner M, Linde-Arias AR, Ponte CG, Velasco L, Koo G, Staruch MJ, Miao S, Parsons WH, Rupprecht K, Slaughter RS, Kaczorowski GJ, Garcia ML. Schmalhofer WA, et al. Biochemistry. 2002 Jun 18;41(24):7781-94. doi: 10.1021/bi025722c. Biochemistry. 2002. PMID: 12056910

3

Purification, characterization, and biosynthesis of margatoxin, a component of Centruroides margaritatus venom that selectively inhibits voltage-dependent potassium channels.

Garcia-Calvo M, Leonard RJ, Novick J, Stevens SP, Schmalhofer W, Kaczorowski GJ, Garcia ML. Garcia-Calvo M, et al. J Biol Chem. 1993 Sep 5;268(25):18866-74. J Biol Chem. 1993. PMID: 8360176 Free article.

4

Pharmacology of potassium channels.

Garcia ML, Hanner M, Knaus HG, Koch R, Schmalhofer W, Slaughter RS, Kaczorowski GJ. Garcia ML, et al. Adv Pharmacol. 1997;39:425-71. doi: 10.1016/s1054-3589(08)60078-2. Adv Pharmacol. 1997. PMID: 9160122 Review. No abstract available.

5

The beta subunit of the high-conductance calcium-activated potassium channel contributes to the high-affinity receptor for charybdotoxin.

Hanner M, Schmalhofer WA, Munujos P, Knaus HG, Kaczorowski GJ, Garcia ML. Hanner M, et al. Among authors: schmalhofer wa. Proc Natl Acad Sci U S A. 1997 Apr 1;94(7):2853-8. doi: 10.1073/pnas.94.7.2853. Proc Natl Acad Sci U S A. 1997. PMID: 9096310 Free PMC article.

6

The beta subunit of the high conductance calcium-activated potassium channel. Identification of residues involved in charybdotoxin binding.

Hanner M, Vianna-Jorge R, Kamassah A, Schmalhofer WA, Knaus HG, Kaczorowski GJ, Garcia ML. Hanner M, et al. Among authors: schmalhofer wa. J Biol Chem. 1998 Jun 26;273(26):16289-96. doi: 10.1074/jbc.273.26.16289. J Biol Chem. 1998. PMID: 9632689 Free article.

7

Identification and biochemical characterization of a novel nortriterpene inhibitor of the human lymphocyte voltage-gated potassium channel, Kv1.3.

Felix JP, Bugianesi RM, Schmalhofer WA, Borris R, Goetz MA, Hensens OD, Bao JM, Kayser F, Parsons WH, Rupprecht K, Garcia ML, Kaczorowski GJ, Slaughter RS. Felix JP, et al. Among authors: schmalhofer wa. Biochemistry. 1999 Apr 20;38(16):4922-30. doi: 10.1021/bi982954w. Biochemistry. 1999. PMID: 10213593

8

Binding of correolide to the K(v)1.3 potassium channel: characterization of the binding domain by site-directed mutagenesis.

Hanner M, Green B, Gao YD, Schmalhofer WA, Matyskiela M, Durand DJ, Felix JP, Linde AR, Bordallo C, Kaczorowski GJ, Kohler M, Garcia ML. Hanner M, et al. Among authors: schmalhofer wa. Biochemistry. 2001 Oct 2;40(39):11687-97. doi: 10.1021/bi0111698. Biochemistry. 2001. PMID: 11570869

9

Benzamide derivatives as blockers of Kv1.3 ion channel.

Miao S, Bao J, Garcia ML, Goulet JL, Hong XJ, Kaczorowski GJ, Kayser F, Koo GC, Kotliar A, Schmalhofer WA, Shah K, Sinclair PJ, Slaughter RS, Springer MS, Staruch MJ, Tsou NN, Wong F, Parsons WH, Rupprecht KM. Miao S, et al. Among authors: schmalhofer wa. Bioorg Med Chem Lett. 2003 Mar 24;13(6):1161-4. doi: 10.1016/s0960-894x(03)00014-3. Bioorg Med Chem Lett. 2003. PMID: 12643934

10

Di-substituted cyclohexyl derivatives bind to two identical sites with positive cooperativity on the voltage-gated potassium channel, K(v)1.3.

Schmalhofer WA, Slaughter RS, Matyskiela M, Felix JP, Tang YS, Rupprecht K, Kaczorowski GJ, Garcia ML. Schmalhofer WA, et al. Biochemistry. 2003 Apr 29;42(16):4733-43. doi: 10.1021/bi034122q. Biochemistry. 2003. PMID: 12705837

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