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Discovery of 4-substituted pyrrolidone butanamides as new agents with significant antiepileptic activity.
J Med Chem. 2004 Jan 29;47(3):530-49. doi: 10.1021/jm030913e.
J Med Chem. 2004.
PMID: 14736235
Discovery of indolone acetamides as novel SV2A ligands with improved potency toward seizure suppression.
Frycia A, Starck JP, Jadot S, Lallemand B, Leclercq K, Lo Brutto P, Matagne A, Verbois V, Mercier J, Kenda B.
Frycia A, et al.
ChemMedChem. 2010 Feb 1;5(2):200-5. doi: 10.1002/cmdc.200900436.
ChemMedChem. 2010.
PMID: 20039359
No abstract available.
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Towards a KCC2 blocker pharmacophore model.
Lebon F, Pégurier C, Ledecq M, Mathieu B, Bosman N, Frycia A, Lengelé S, Dhurke K, Kanduluru AK, Meunier S, Wagner A, Wolff C, Provins L.
Lebon F, et al.
Bioorg Med Chem Lett. 2012 Jun 15;22(12):3978-82. doi: 10.1016/j.bmcl.2012.04.097. Epub 2012 Apr 30.
Bioorg Med Chem Lett. 2012.
PMID: 22608391
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Synthesis and biological evaluation of constrained analogues of the opioid peptide H-Tyr-D-Ala-Phe-Gly-NH2 using the 4-amino-2-benzazepin-3-one scaffold.
Ballet S, Frycia A, Piron J, Chung NN, Schiller PW, Kosson P, Lipkowski AW, Tourwé D.
Ballet S, et al.
J Pept Res. 2005 Nov;66(5):222-30. doi: 10.1111/j.1399-3011.2005.00291.x.
J Pept Res. 2005.
PMID: 16218989
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Conformational restriction of Tyr and Phe side chains in opioid peptides: information about preferred and bioactive side-chain topology.
Tourwé D, Verschueren K, Frycia A, Davis P, Porreca F, Hruby VJ, Toth G, Jaspers H, Verheyden P, Van Binst G.
Tourwé D, et al.
Biopolymers. 1996 Jan;38(1):1-12. doi: 10.1002/(sici)1097-0282(199601)38:1<1::aid-bip1>3.0.co;2-#.
Biopolymers. 1996.
PMID: 8679939
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