Schaap MM - Search Results

1

Dominant-negative but not gain-of-function effects of a p53.R270H mutation in mouse epithelium tissue after DNA damage.

Wijnhoven SW, Speksnijder EN, Liu X, Zwart E, vanOostrom CT, Beems RB, Hoogervorst EM, Schaap MM, Attardi LD, Jacks T, van Steeg H, Jonkers J, de Vries A. Wijnhoven SW, et al. Among authors: schaap mm. Cancer Res. 2007 May 15;67(10):4648-56. doi: 10.1158/0008-5472.CAN-06-4681. Cancer Res. 2007. PMID: 17510390

2

Mice expressing a mammary gland-specific R270H mutation in the p53 tumor suppressor gene mimic human breast cancer development.

Wijnhoven SW, Zwart E, Speksnijder EN, Beems RB, Olive KP, Tuveson DA, Jonkers J, Schaap MM, van den Berg J, Jacks T, van Steeg H, de Vries A. Wijnhoven SW, et al. Among authors: schaap mm. Cancer Res. 2005 Sep 15;65(18):8166-73. doi: 10.1158/0008-5472.CAN-05-1650. Cancer Res. 2005. PMID: 16166291

3

lacZ mouse embryonic fibroblasts detect both clastogens and mutagens.

Mahabir AG, Zwart E, Schaap M, van Benthem J, de Vries A, Hernandez LG, Hendriksen CF, van Steeg H. Mahabir AG, et al. Mutat Res. 2009 Jun 18;666(1-2):50-6. doi: 10.1016/j.mrfmmm.2009.04.005. Epub 2009 Apr 23. Mutat Res. 2009. PMID: 19393670

4

Delayed expression of apoptotic and cell-cycle control genes in carcinogen-exposed bladders of mice lacking p53.S389 phosphorylation.

Bruins W, Jonker MJ, Bruning O, Pennings JL, Schaap MM, Hoogervorst EM, van Steeg H, Breit TM, de Vries A. Bruins W, et al. Among authors: schaap mm. Carcinogenesis. 2007 Aug;28(8):1814-23. doi: 10.1093/carcin/bgm041. Epub 2007 Feb 21. Carcinogenesis. 2007. PMID: 17317680

5

Detection of genotoxic and non-genotoxic carcinogens in Xpc(-/-)p53(+/-) mice.

Melis JP, Speksnijder EN, Kuiper RV, Salvatori DC, Schaap MM, Maas S, Robinson J, Verhoef A, van Benthem J, Luijten M, van Steeg H. Melis JP, et al. Among authors: schaap mm. Toxicol Appl Pharmacol. 2013 Jan 15;266(2):289-97. doi: 10.1016/j.taap.2012.11.004. Epub 2012 Nov 12. Toxicol Appl Pharmacol. 2013. PMID: 23153559

6

DNA-repair-deficient Rad54/Rad54B mice are more sensitive to clastogens than wild-type mice.

Mahabir AG, Schaap M, Theunissen P, van Benthem J, Essers J, de Vries A, Hendriksen CF, van Steeg H. Mahabir AG, et al. Toxicol Lett. 2008 Dec 15;183(1-3):112-7. doi: 10.1016/j.toxlet.2008.10.005. Epub 2008 Oct 21. Toxicol Lett. 2008. PMID: 19007869

7

Proliferating primary hepatocytes from the pUR288 lacZ plasmid mouse are valuable tools for genotoxicity assessment in vitro.

Zwart EP, Schaap MM, van den Dungen MW, Braakhuis HM, White PA, van Steeg H, van Benthem J, Luijten M. Zwart EP, et al. Among authors: schaap mm. Environ Mol Mutagen. 2012 Jun;53(5):1-8. doi: 10.1002/em.21700. Epub 2012 May 23. Environ Mol Mutagen. 2012. PMID: 22619112

8

Ozone induces clear cellular and molecular responses in the mouse lung independently of the transcription-coupled repair status.

Kooter IM, Pennings JL, Fokkens PH, Leseman DL, Boere AJ, Gerlofs-Nijland ME, Cassee FR, Schalk JA, Orzechowski TJ, Schaap MM, Breit TM, Dormans JA, van Oostrom CT, de Vries A, van Steeg H. Kooter IM, et al. Among authors: schaap mm. J Appl Physiol (1985). 2007 Mar;102(3):1185-92. doi: 10.1152/japplphysiol.00796.2006. Epub 2006 Nov 9. J Appl Physiol (1985). 2007. PMID: 17095637 Free article.

9

Finding transcriptomics biomarkers for in vivo identification of (non-)genotoxic carcinogens using wild-type and Xpa/p53 mutant mouse models.

Jonker MJ, Bruning O, van Iterson M, Schaap MM, van der Hoeven TV, Vrieling H, Beems RB, de Vries A, van Steeg H, Breit TM, Luijten M. Jonker MJ, et al. Among authors: schaap mm. Carcinogenesis. 2009 Oct;30(10):1805-12. doi: 10.1093/carcin/bgp190. Epub 2009 Aug 20. Carcinogenesis. 2009. PMID: 19696161

10

Comparison of clastogen-induced gene expression profiles in wild-type and DNA repair-deficient Rad54/Rad54B cells.

Mahabir AG, Schaap MM, Pennings JL, van Benthem J, Hendriksen CF, van Steeg H. Mahabir AG, et al. Among authors: schaap mm. BMC Genomics. 2010 Jan 12;11:24. doi: 10.1186/1471-2164-11-24. BMC Genomics. 2010. PMID: 20067618 Free PMC article.

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