de Vries A - Search Results

1

High incidence of protein-truncating TP53 mutations in BRCA1-related breast cancer.

Holstege H, Joosse SA, van Oostrom CT, Nederlof PM, de Vries A, Jonkers J. Holstege H, et al. Among authors: de vries a. Cancer Res. 2009 Apr 15;69(8):3625-33. doi: 10.1158/0008-5472.CAN-08-3426. Epub 2009 Mar 31. Cancer Res. 2009. PMID: 19336573

2

Lack of p53 Ser389 phosphorylation predisposes mice to develop 2-acetylaminofluorene-induced bladder tumors but not ionizing radiation-induced lymphomas.

Hoogervorst EM, Bruins W, Zwart E, van Oostrom CT, van den Aardweg GJ, Beems RB, van den Berg J, Jacks T, van Steeg H, de Vries A. Hoogervorst EM, et al. Among authors: de vries a. Cancer Res. 2005 May 1;65(9):3610-6. doi: 10.1158/0008-5472.CAN-04-4328. Cancer Res. 2005. PMID: 15867355

3

Dominant-negative but not gain-of-function effects of a p53.R270H mutation in mouse epithelium tissue after DNA damage.

Wijnhoven SW, Speksnijder EN, Liu X, Zwart E, vanOostrom CT, Beems RB, Hoogervorst EM, Schaap MM, Attardi LD, Jacks T, van Steeg H, Jonkers J, de Vries A. Wijnhoven SW, et al. Among authors: de vries a. Cancer Res. 2007 May 15;67(10):4648-56. doi: 10.1158/0008-5472.CAN-06-4681. Cancer Res. 2007. PMID: 17510390

4

Mammary gland-specific ablation of focal adhesion kinase reduces the incidence of p53-mediated mammary tumour formation.

van Miltenburg MH, van Nimwegen MJ, Tijdens I, Lalai R, Kuiper R, Klarenbeek S, Schouten PC, de Vries A, Jonkers J, van de Water B. van Miltenburg MH, et al. Among authors: de vries a. Br J Cancer. 2014 May 27;110(11):2747-55. doi: 10.1038/bjc.2014.219. Epub 2014 May 8. Br J Cancer. 2014. PMID: 24809783 Free PMC article.

5

Targeted point mutations of p53 lead to dominant-negative inhibition of wild-type p53 function.

de Vries A, Flores ER, Miranda B, Hsieh HM, van Oostrom CT, Sage J, Jacks T. de Vries A, et al. Proc Natl Acad Sci U S A. 2002 Mar 5;99(5):2948-53. doi: 10.1073/pnas.052713099. Epub 2002 Feb 26. Proc Natl Acad Sci U S A. 2002. PMID: 11867759 Free PMC article.

6

p53 heterozygosity results in an increased 2-acetylaminofluorene-induced urinary bladder but not liver tumor response in DNA repair-deficient Xpa mice.

Hoogervorst EM, van Oostrom CT, Beems RB, van Benthem J, Gielis S, Vermeulen JP, Wester PW, Vos JG, de Vries A, van Steeg H. Hoogervorst EM, et al. Among authors: de vries a. Cancer Res. 2004 Aug 1;64(15):5118-26. doi: 10.1158/0008-5472.CAN-04-0350. Cancer Res. 2004. PMID: 15289314

7

Mice expressing a mammary gland-specific R270H mutation in the p53 tumor suppressor gene mimic human breast cancer development.

Wijnhoven SW, Zwart E, Speksnijder EN, Beems RB, Olive KP, Tuveson DA, Jonkers J, Schaap MM, van den Berg J, Jacks T, van Steeg H, de Vries A. Wijnhoven SW, et al. Among authors: de vries a. Cancer Res. 2005 Sep 15;65(18):8166-73. doi: 10.1158/0008-5472.CAN-05-1650. Cancer Res. 2005. PMID: 16166291

8

Defective apoptosis and B-cell lymphomas in mice with p53 point mutation at Ser 23.

MacPherson D, Kim J, Kim T, Rhee BK, Van Oostrom CT, DiTullio RA, Venere M, Halazonetis TD, Bronson R, De Vries A, Fleming M, Jacks T. MacPherson D, et al. Among authors: de vries a. EMBO J. 2004 Sep 15;23(18):3689-99. doi: 10.1038/sj.emboj.7600363. Epub 2004 Sep 2. EMBO J. 2004. PMID: 15343266 Free PMC article.

9

Elevated frequencies of benzo(a)pyrene-induced Hprt mutations in internal tissue of XPA-deficient mice.

Bol SA, van Steeg H, Jansen JG, Van Oostrom C, de Vries A, de Groot AJ, Tates AD, Vrieling H, van Zeeland AA, Mullenders LH. Bol SA, et al. Among authors: de groot aj, de vries a. Cancer Res. 1998 Jul 1;58(13):2850-6. Cancer Res. 1998. PMID: 9661901

Recently, mice have been generated via gene targeting that are deficient in the expression of the XPA gene [A. de Vries et al., Nature (Lond.), 377: 169-173, 1995]. We have assessed the consequences of defective NER for mutagenesis in normal and XPA mice expo …

Recently, mice have been generated via gene targeting that are deficient in the expression of the XPA gene [A. de Vries …

10

2-AAF-induced tumor development in nucleotide excision repair-deficient mice is associated with a defect in global genome repair but not with transcription coupled repair.

Hoogervorst EM, van Oostrom CT, Beems RB, van Benthem J, van den Berg J, van Kreijl CF, Vos JG, de Vries A, van Steeg H. Hoogervorst EM, et al. Among authors: de vries a. DNA Repair (Amst). 2005 Jan 2;4(1):3-9. doi: 10.1016/j.dnarep.2004.08.009. DNA Repair (Amst). 2005. PMID: 15533832

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