Liu KG - Search Results

1

1-Sulfonylindazoles as potent and selective 5-HT6 ligands.

Liu KG, Lo JR, Comery TA, Zhang GM, Zhang JY, Kowal DM, Smith DL, Di L, Kerns EH, Schechter LE, Robichaud AJ. Liu KG, et al. Bioorg Med Chem Lett. 2009 May 1;19(9):2413-5. doi: 10.1016/j.bmcl.2009.03.071. Epub 2009 Mar 21. Bioorg Med Chem Lett. 2009. PMID: 19345582

2

A regiospecific synthesis of a series of 1-sulfonyl azepinoindoles as potent 5-HT6 ligands.

Liu KG, Lo JR, Comery TA, Zhang GM, Zhang JY, Kowal DM, Smith DL, Di L, Kerns EH, Schechter LE, Robichaud AJ. Liu KG, et al. Bioorg Med Chem Lett. 2008 Jul 15;18(14):3929-31. doi: 10.1016/j.bmcl.2008.06.030. Epub 2008 Jun 13. Bioorg Med Chem Lett. 2008. PMID: 18583130

3

Identification of a series of benzoxazoles as potent 5-HT6 ligands.

Liu KG, Lo JR, Comery TA, Zhang GM, Zhang JY, Kowal DM, Smith DL, Di L, Kerns EH, Schechter LE, Robichaud AJ. Liu KG, et al. Bioorg Med Chem Lett. 2009 Feb 15;19(4):1115-7. doi: 10.1016/j.bmcl.2008.12.107. Epub 2009 Jan 3. Bioorg Med Chem Lett. 2009. PMID: 19152787

4

Identification of a novel series of 3-piperidinyl-5-sulfonylindazoles as potent 5-HT6 ligands.

Liu KG, Lo JR, Comery TA, Zhang GM, Zhang JY, Kowal DM, Smith DL, Di L, Kerns EH, Schechter LE, Robichaud AJ. Liu KG, et al. Bioorg Med Chem Lett. 2009 Jun 15;19(12):3214-6. doi: 10.1016/j.bmcl.2009.04.108. Epub 2009 May 3. Bioorg Med Chem Lett. 2009. PMID: 19433358

5

5-Piperazinyl-3-sulfonylindazoles as potent and selective 5-hydroxytryptamine-6 antagonists.

Liu KG, Robichaud AJ, Bernotas RC, Yan Y, Lo JR, Zhang MY, Hughes ZA, Huselton C, Zhang GM, Zhang JY, Kowal DM, Smith DL, Schechter LE, Comery TA. Liu KG, et al. J Med Chem. 2010 Nov 11;53(21):7639-46. doi: 10.1021/jm1007825. J Med Chem. 2010. PMID: 20932009

6

Identification of 3-sulfonylindazole derivatives as potent and selective 5-HT(6) antagonists.

Liu KG, Robichaud AJ, Greenfield AA, Lo JR, Grosanu C, Mattes JF, Cai Y, Zhang GM, Zhang JY, Kowal DM, Smith DL, Di L, Kerns EH, Schechter LE, Comery TA. Liu KG, et al. Bioorg Med Chem. 2011 Jan 1;19(1):650-62. doi: 10.1016/j.bmc.2010.10.033. Epub 2010 Oct 20. Bioorg Med Chem. 2011. PMID: 21093272

7

Rearrangement of 3,3-disubstituted indolenines and synthesis of 2,3-substituted indoles.

Liu KG, Robichaud AJ, Lo JR, Mattes JF, Cai Y. Liu KG, et al. Org Lett. 2006 Dec 7;8(25):5769-71. doi: 10.1021/ol0623567. Org Lett. 2006. PMID: 17134268

8

5-HT6 medicinal chemistry.

Liu KG, Robichaud AJ. Liu KG, et al. Int Rev Neurobiol. 2010;94:1-34. doi: 10.1016/B978-0-12-384976-2.00001-0. Int Rev Neurobiol. 2010. PMID: 21081200 Review. No abstract available.

9

Tricyclic thiazolopyrazole derivatives as metabotropic glutamate receptor 4 positive allosteric modulators.

Hong SP, Liu KG, Ma G, Sabio M, Uberti MA, Bacolod MD, Peterson J, Zou ZZ, Robichaud AJ, Doller D. Hong SP, et al. Among authors: liu kg. J Med Chem. 2011 Jul 28;54(14):5070-81. doi: 10.1021/jm200290z. Epub 2011 Jul 1. J Med Chem. 2011. PMID: 21688779

10

4-(1-Phenyl-1H-pyrazol-4-yl)quinolines as novel, selective and brain penetrant metabotropic glutamate receptor 4 positive allosteric modulators.

Jimenez HN, Liu KG, Hong SP, Reitman MS, Uberti MA, Bacolod MD, Cajina M, Nattini M, Sabio M, Doller D. Jimenez HN, et al. Among authors: liu kg. Bioorg Med Chem Lett. 2012 May 1;22(9):3235-9. doi: 10.1016/j.bmcl.2012.03.032. Epub 2012 Mar 15. Bioorg Med Chem Lett. 2012. PMID: 22465637

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