Zhang JY - Search Results

1

1-Sulfonylindazoles as potent and selective 5-HT6 ligands.

Liu KG, Lo JR, Comery TA, Zhang GM, Zhang JY, Kowal DM, Smith DL, Di L, Kerns EH, Schechter LE, Robichaud AJ. Liu KG, et al. Among authors: zhang gm, zhang jy. Bioorg Med Chem Lett. 2009 May 1;19(9):2413-5. doi: 10.1016/j.bmcl.2009.03.071. Epub 2009 Mar 21. Bioorg Med Chem Lett. 2009. PMID: 19345582

2

A regiospecific synthesis of a series of 1-sulfonyl azepinoindoles as potent 5-HT6 ligands.

Liu KG, Lo JR, Comery TA, Zhang GM, Zhang JY, Kowal DM, Smith DL, Di L, Kerns EH, Schechter LE, Robichaud AJ. Liu KG, et al. Among authors: zhang gm, zhang jy. Bioorg Med Chem Lett. 2008 Jul 15;18(14):3929-31. doi: 10.1016/j.bmcl.2008.06.030. Epub 2008 Jun 13. Bioorg Med Chem Lett. 2008. PMID: 18583130

3

Identification of a series of benzoxazoles as potent 5-HT6 ligands.

Liu KG, Lo JR, Comery TA, Zhang GM, Zhang JY, Kowal DM, Smith DL, Di L, Kerns EH, Schechter LE, Robichaud AJ. Liu KG, et al. Among authors: zhang gm, zhang jy. Bioorg Med Chem Lett. 2009 Feb 15;19(4):1115-7. doi: 10.1016/j.bmcl.2008.12.107. Epub 2009 Jan 3. Bioorg Med Chem Lett. 2009. PMID: 19152787

4

Identification of a novel series of 3-piperidinyl-5-sulfonylindazoles as potent 5-HT6 ligands.

Liu KG, Lo JR, Comery TA, Zhang GM, Zhang JY, Kowal DM, Smith DL, Di L, Kerns EH, Schechter LE, Robichaud AJ. Liu KG, et al. Among authors: zhang gm, zhang jy. Bioorg Med Chem Lett. 2009 Jun 15;19(12):3214-6. doi: 10.1016/j.bmcl.2009.04.108. Epub 2009 May 3. Bioorg Med Chem Lett. 2009. PMID: 19433358

5

5-Piperazinyl-3-sulfonylindazoles as potent and selective 5-hydroxytryptamine-6 antagonists.

Liu KG, Robichaud AJ, Bernotas RC, Yan Y, Lo JR, Zhang MY, Hughes ZA, Huselton C, Zhang GM, Zhang JY, Kowal DM, Smith DL, Schechter LE, Comery TA. Liu KG, et al. Among authors: zhang gm, zhang jy, zhang my. J Med Chem. 2010 Nov 11;53(21):7639-46. doi: 10.1021/jm1007825. J Med Chem. 2010. PMID: 20932009

6

Identification of 3-sulfonylindazole derivatives as potent and selective 5-HT(6) antagonists.

Liu KG, Robichaud AJ, Greenfield AA, Lo JR, Grosanu C, Mattes JF, Cai Y, Zhang GM, Zhang JY, Kowal DM, Smith DL, Di L, Kerns EH, Schechter LE, Comery TA. Liu KG, et al. Among authors: zhang gm, zhang jy. Bioorg Med Chem. 2011 Jan 1;19(1):650-62. doi: 10.1016/j.bmc.2010.10.033. Epub 2010 Oct 20. Bioorg Med Chem. 2011. PMID: 21093272

7

Tetrahydrocarbazole-based serotonin reuptake inhibitor/dopamine D2 partial agonists for the potential treatment of schizophrenia.

Rotella DP, McFarlane GR, Greenfield A, Grosanu C, Robichaud AJ, Denny RA, Feenstra RW, Núñez-García S, Reinders JH, Neut Mv, McCreary A, Kruse CG, Sullivan K, Pruthi F, Lai M, Zhang J, Kowal DM, Carrick T, Grauer SM, Navarra RL, Graf R, Brennan J, Marquis KL, Pausch MH. Rotella DP, et al. Bioorg Med Chem Lett. 2009 Oct 1;19(19):5552-5. doi: 10.1016/j.bmcl.2009.08.050. Epub 2009 Aug 15. Bioorg Med Chem Lett. 2009. PMID: 19720528

8

5-Cyclic amine-3-arylsulfonylindazoles as novel 5-HT6 receptor antagonists.

Haydar SN, Yun H, Andrae PM, Mattes J, Zhang J, Kramer A, Smith DL, Huselton C, Graf R, Aschmies S, Schechter LE, Comery TA, Robichaud AJ. Haydar SN, et al. J Med Chem. 2010 Mar 25;53(6):2521-7. doi: 10.1021/jm901674f. J Med Chem. 2010. PMID: 20170099

9

Potent dihydroquinolinone dopamine D2 partial agonist/serotonin reuptake inhibitors for the treatment of schizophrenia.

Yan Y, Zhou P, Rotella DP, Feenstra R, Kruse CG, Reinders JH, van der Neut M, Lai M, Zhang J, Kowal DM, Carrick T, Marquis KL, Pausch MH, Robichaud AJ. Yan Y, et al. Bioorg Med Chem Lett. 2010 May 1;20(9):2983-6. doi: 10.1016/j.bmcl.2010.02.105. Epub 2010 Mar 3. Bioorg Med Chem Lett. 2010. PMID: 20347298

10

Characterization of the 5-HT6 receptor coupled to Ca2+ signaling using an enabling chimeric G-protein.

Zhang JY, Nawoschik S, Kowal D, Smith D, Spangler T, Ochalski R, Schechter L, Dunlop J. Zhang JY, et al. Eur J Pharmacol. 2003 Jul 4;472(1-2):33-8. doi: 10.1016/s0014-2999(03)01855-7. Eur J Pharmacol. 2003. PMID: 12860470

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