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Targeting GIPC/synectin in pancreatic cancer inhibits tumor growth.
Muders MH, Vohra PK, Dutta SK, Wang E, Ikeda Y, Wang L, Udugamasooriya DG, Memic A, Rupasinghe CN, Baretton GB, Aust DE, Langer S, Datta K, Simons M, Spaller MR, Mukhopadhyay D. Muders MH, et al. Among authors: simons m. Clin Cancer Res. 2009 Jun 15;15(12):4095-103. doi: 10.1158/1078-0432.CCR-08-2837. Epub 2009 Jun 9. Clin Cancer Res. 2009. PMID: 19509165 Free PMC article.
Cardiomyopathy and Worsened Ischemic Heart Failure in SM22-α Cre-Mediated Neuropilin-1 Null Mice: Dysregulation of PGC1α and Mitochondrial Homeostasis.
Wang Y, Cao Y, Yamada S, Thirunavukkarasu M, Nin V, Joshi M, Rishi MT, Bhattacharya S, Camacho-Pereira J, Sharma AK, Shameer K, Kocher JP, Sanchez JA, Wang E, Hoeppner LH, Dutta SK, Leof EB, Shah V, Claffey KP, Chini EN, Simons M, Terzic A, Maulik N, Mukhopadhyay D. Wang Y, et al. Among authors: simons m. Arterioscler Thromb Vasc Biol. 2015 Jun;35(6):1401-12. doi: 10.1161/ATVBAHA.115.305566. Epub 2015 Apr 16. Arterioscler Thromb Vasc Biol. 2015. PMID: 25882068 Free PMC article.
Synectin promotes fibrogenesis by regulating PDGFR isoforms through distinct mechanisms.
Drinane MC, Yaqoob U, Yu H, Luo F, Greuter T, Arab JP, Kostallari E, Verma VK, Maiers J, De Assuncao TM, Simons M, Mukhopadhyay D, Kisseleva T, Brenner DA, Urrutia R, Lomberk G, Gao Y, Ligresti G, Tschumperlin DJ, Revzin A, Cao S, Shah VH. Drinane MC, et al. Among authors: simons m. JCI Insight. 2017 Dec 21;2(24):e92821. doi: 10.1172/jci.insight.92821. JCI Insight. 2017. PMID: 29263300 Free PMC article.
Synectin-dependent regulation of arterial maturation.
Paye JM, Phng LK, Lanahan AA, Gerhard H, Simons M. Paye JM, et al. Among authors: simons m. Dev Dyn. 2009 Mar;238(3):604-10. doi: 10.1002/dvdy.21880. Dev Dyn. 2009. PMID: 19235722 Free PMC article.
ERK1/2-Akt1 crosstalk regulates arteriogenesis in mice and zebrafish.
Ren B, Deng Y, Mukhopadhyay A, Lanahan AA, Zhuang ZW, Moodie KL, Mulligan-Kehoe MJ, Byzova TV, Peterson RT, Simons M. Ren B, et al. Among authors: simons m. J Clin Invest. 2010 Apr;120(4):1217-28. doi: 10.1172/JCI39837. Epub 2010 Mar 8. J Clin Invest. 2010. PMID: 20237411 Free PMC article.
1,484 results