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Page 1
Expression of neonatal Fc receptor in the eye.
Powner MB, McKenzie JA, Christianson GJ, Roopenian DC, Fruttiger M. Powner MB, et al. Among authors: christianson gj. Invest Ophthalmol Vis Sci. 2014 Mar 19;55(3):1607-15. doi: 10.1167/iovs.13-12574. Invest Ophthalmol Vis Sci. 2014. PMID: 24550358 Free PMC article.
A human endothelial cell-based recycling assay for screening of FcRn targeted molecules.
Grevys A, Nilsen J, Sand KMK, Daba MB, Øynebråten I, Bern M, McAdam MB, Foss S, Schlothauer T, Michaelsen TE, Christianson GJ, Roopenian DC, Blumberg RS, Sandlie I, Andersen JT. Grevys A, et al. Among authors: christianson gj. Nat Commun. 2018 Feb 12;9(1):621. doi: 10.1038/s41467-018-03061-x. Nat Commun. 2018. PMID: 29434196 Free PMC article.
Hepatic FcRn regulates albumin homeostasis and susceptibility to liver injury.
Pyzik M, Rath T, Kuo TT, Win S, Baker K, Hubbard JJ, Grenha R, Gandhi A, Krämer TD, Mezo AR, Taylor ZS, McDonnell K, Nienaber V, Andersen JT, Mizoguchi A, Blumberg L, Purohit S, Jones SD, Christianson G, Lencer WI, Sandlie I, Kaplowitz N, Roopenian DC, Blumberg RS. Pyzik M, et al. Proc Natl Acad Sci U S A. 2017 Apr 4;114(14):E2862-E2871. doi: 10.1073/pnas.1618291114. Epub 2017 Mar 22. Proc Natl Acad Sci U S A. 2017. PMID: 28330995 Free PMC article.
An engineered human albumin enhances half-life and transmucosal delivery when fused to protein-based biologics.
Bern M, Nilsen J, Ferrarese M, Sand KMK, Gjølberg TT, Lode HE, Davidson RJ, Camire RM, Bækkevold ES, Foss S, Grevys A, Dalhus B, Wilson J, Høydahl LS, Christianson GJ, Roopenian DC, Schlothauer T, Michaelsen TE, Moe MC, Lombardi S, Pinotti M, Sandlie I, Branchini A, Andersen JT. Bern M, et al. Among authors: christianson gj. Sci Transl Med. 2020 Oct 14;12(565):eabb0580. doi: 10.1126/scitranslmed.abb0580. Sci Transl Med. 2020. PMID: 33055243
Blocking FcRn in humans reduces circulating IgG levels and inhibits IgG immune complex-mediated immune responses.
Blumberg LJ, Humphries JE, Jones SD, Pearce LB, Holgate R, Hearn A, Cheung J, Mahmood A, Del Tito B, Graydon JS, Stolz LE, Bitonti A, Purohit S, de Graaf D, Kacena K, Andersen JT, Christianson GJ, Roopenian DC, Hubbard JJ, Gandhi AK, Lasseter K, Pyzik M, Blumberg RS. Blumberg LJ, et al. Among authors: christianson gj. Sci Adv. 2019 Dec 18;5(12):eaax9586. doi: 10.1126/sciadv.aax9586. eCollection 2019 Dec. Sci Adv. 2019. PMID: 31897428 Free PMC article. Clinical Trial.
55 results