Superfine R - Search Results

1

Haemodynamic and extracellular matrix cues regulate the mechanical phenotype and stiffness of aortic endothelial cells.

Collins C, Osborne LD, Guilluy C, Chen Z, O'Brien ET 3rd, Reader JS, Burridge K, Superfine R, Tzima E. Collins C, et al. Among authors: superfine r. Nat Commun. 2014 Jun 11;5:3984. doi: 10.1038/ncomms4984. Nat Commun. 2014. PMID: 24917553 Free PMC article.

2

Localized tensional forces on PECAM-1 elicit a global mechanotransduction response via the integrin-RhoA pathway.

Collins C, Guilluy C, Welch C, O'Brien ET, Hahn K, Superfine R, Burridge K, Tzima E. Collins C, et al. Among authors: superfine r. Curr Biol. 2012 Nov 20;22(22):2087-94. doi: 10.1016/j.cub.2012.08.051. Epub 2012 Oct 18. Curr Biol. 2012. PMID: 23084990 Free PMC article.

3

Isolated nuclei adapt to force and reveal a mechanotransduction pathway in the nucleus.

Guilluy C, Osborne LD, Van Landeghem L, Sharek L, Superfine R, Garcia-Mata R, Burridge K. Guilluy C, et al. Among authors: superfine r. Nat Cell Biol. 2014 Apr;16(4):376-81. doi: 10.1038/ncb2927. Epub 2014 Mar 9. Nat Cell Biol. 2014. PMID: 24609268 Free PMC article.

4

The Rho GEFs LARG and GEF-H1 regulate the mechanical response to force on integrins.

Guilluy C, Swaminathan V, Garcia-Mata R, O'Brien ET, Superfine R, Burridge K. Guilluy C, et al. Among authors: superfine r. Nat Cell Biol. 2011 Jun;13(6):722-7. doi: 10.1038/ncb2254. Epub 2011 May 15. Nat Cell Biol. 2011. PMID: 21572419 Free PMC article.

5

The vinculin C-terminal hairpin mediates F-actin bundle formation, focal adhesion, and cell mechanical properties.

Shen K, Tolbert CE, Guilluy C, Swaminathan VS, Berginski ME, Burridge K, Superfine R, Campbell SL. Shen K, et al. Among authors: superfine r. J Biol Chem. 2011 Dec 30;286(52):45103-15. doi: 10.1074/jbc.M111.244293. Epub 2011 Nov 3. J Biol Chem. 2011. PMID: 22052910 Free PMC article.

6

HIF1α and HIF2α independently activate SRC to promote melanoma metastases.

Hanna SC, Krishnan B, Bailey ST, Moschos SJ, Kuan PF, Shimamura T, Osborne LD, Siegel MB, Duncan LM, O'Brien ET 3rd, Superfine R, Miller CR, Simon MC, Wong KK, Kim WY. Hanna SC, et al. Among authors: superfine r. J Clin Invest. 2013 May;123(5):2078-93. doi: 10.1172/JCI66715. Epub 2013 Apr 8. J Clin Invest. 2013. PMID: 23563312 Free PMC article.

7

The RhoA guanine nucleotide exchange factor, LARG, mediates ICAM-1-dependent mechanotransduction in endothelial cells to stimulate transendothelial migration.

Lessey-Morillon EC, Osborne LD, Monaghan-Benson E, Guilluy C, O'Brien ET, Superfine R, Burridge K. Lessey-Morillon EC, et al. Among authors: superfine r. J Immunol. 2014 Apr 1;192(7):3390-8. doi: 10.4049/jimmunol.1302525. Epub 2014 Feb 28. J Immunol. 2014. PMID: 24585879 Free PMC article.

8

Phosphorylation at Y1065 in vinculin mediates actin bundling, cell spreading, and mechanical responses to force.

Tolbert CE, Thompson PM, Superfine R, Burridge K, Campbell SL. Tolbert CE, et al. Among authors: superfine r. Biochemistry. 2014 Sep 2;53(34):5526-36. doi: 10.1021/bi500678x. Epub 2014 Aug 21. Biochemistry. 2014. PMID: 25115937 Free PMC article.

9

TGF-β regulates LARG and GEF-H1 during EMT to affect stiffening response to force and cell invasion.

Osborne LD, Li GZ, How T, O'Brien ET, Blobe GC, Superfine R, Mythreye K. Osborne LD, et al. Among authors: superfine r. Mol Biol Cell. 2014 Nov 5;25(22):3528-40. doi: 10.1091/mbc.E14-05-1015. Epub 2014 Aug 20. Mol Biol Cell. 2014. PMID: 25143398 Free PMC article.

10

Vinculin and metavinculin exhibit distinct effects on focal adhesion properties, cell migration, and mechanotransduction.

Lee HT, Sharek L, O'Brien ET, Urbina FL, Gupton SL, Superfine R, Burridge K, Campbell SL. Lee HT, et al. Among authors: superfine r. PLoS One. 2019 Sep 4;14(9):e0221962. doi: 10.1371/journal.pone.0221962. eCollection 2019. PLoS One. 2019. PMID: 31483833 Free PMC article.

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