Yarden Y - Search Results

1

The ErbB4 CYT2 variant protects EGFR from ligand-induced degradation to enhance cancer cell motility.

Kiuchi T, Ortiz-Zapater E, Monypenny J, Matthews DR, Nguyen LK, Barbeau J, Coban O, Lawler K, Burford B, Rolfe DJ, de Rinaldis E, Dafou D, Simpson MA, Woodman N, Pinder S, Gillett CE, Devauges V, Poland SP, Fruhwirth G, Marra P, Boersma YL, Plückthun A, Gullick WJ, Yarden Y, Santis G, Winn M, Kholodenko BN, Martin-Fernandez ML, Parker P, Tutt A, Ameer-Beg SM, Ng T. Kiuchi T, et al. Among authors: yarden y. Sci Signal. 2014 Aug 19;7(339):ra78. doi: 10.1126/scisignal.2005157. Sci Signal. 2014. PMID: 25140053

2

Molecular mechanisms underlying ErbB2/HER2 action in breast cancer.

Harari D, Yarden Y. Harari D, et al. Among authors: yarden y. Oncogene. 2000 Dec 11;19(53):6102-14. doi: 10.1038/sj.onc.1203973. Oncogene. 2000. PMID: 11156523 Review.

3

The EGFR family and its ligands in human cancer. signalling mechanisms and therapeutic opportunities.

Yarden Y. Yarden Y. Eur J Cancer. 2001 Sep;37 Suppl 4:S3-8. doi: 10.1016/s0959-8049(01)00230-1. Eur J Cancer. 2001. PMID: 11597398 Review.

4

Biology of HER2 and its importance in breast cancer.

Yarden Y. Yarden Y. Oncology. 2001;61 Suppl 2:1-13. doi: 10.1159/000055396. Oncology. 2001. PMID: 11694782 Review.

5

A mutant EGF-receptor defective in ubiquitylation and endocytosis unveils a role for Grb2 in negative signaling.

Waterman H, Katz M, Rubin C, Shtiegman K, Lavi S, Elson A, Jovin T, Yarden Y. Waterman H, et al. Among authors: yarden y. EMBO J. 2002 Feb 1;21(3):303-13. doi: 10.1093/emboj/21.3.303. EMBO J. 2002. PMID: 11823423 Free PMC article.

6

Drug-induced ubiquitylation and degradation of ErbB receptor tyrosine kinases: implications for cancer therapy.

Citri A, Alroy I, Lavi S, Rubin C, Xu W, Grammatikakis N, Patterson C, Neckers L, Fry DW, Yarden Y. Citri A, et al. Among authors: yarden y. EMBO J. 2002 May 15;21(10):2407-17. doi: 10.1093/emboj/21.10.2407. EMBO J. 2002. PMID: 12006493 Free PMC article.

7

LRIG1 restricts growth factor signaling by enhancing receptor ubiquitylation and degradation.

Gur G, Rubin C, Katz M, Amit I, Citri A, Nilsson J, Amariglio N, Henriksson R, Rechavi G, Hedman H, Wides R, Yarden Y. Gur G, et al. Among authors: yarden y. EMBO J. 2004 Aug 18;23(16):3270-81. doi: 10.1038/sj.emboj.7600342. Epub 2004 Jul 29. EMBO J. 2004. PMID: 15282549 Free PMC article.

8

In vitro and in vivo assays of monoubiquitination of receptor tyrosine kinases.

Katz M, Mosesson Y, Yarden Y. Katz M, et al. Among authors: yarden y. Methods Mol Biol. 2006;327:115-29. doi: 10.1385/1-59745-012-X:115. Methods Mol Biol. 2006. PMID: 16780216

9

Defective ubiquitinylation of EGFR mutants of lung cancer confers prolonged signaling.

Shtiegman K, Kochupurakkal BS, Zwang Y, Pines G, Starr A, Vexler A, Citri A, Katz M, Lavi S, Ben-Basat Y, Benjamin S, Corso S, Gan J, Yosef RB, Giordano S, Yarden Y. Shtiegman K, et al. Among authors: yarden y. Oncogene. 2007 Oct 25;26(49):6968-78. doi: 10.1038/sj.onc.1210503. Epub 2007 May 7. Oncogene. 2007. PMID: 17486068

10

A reciprocal tensin-3-cten switch mediates EGF-driven mammary cell migration.

Katz M, Amit I, Citri A, Shay T, Carvalho S, Lavi S, Milanezi F, Lyass L, Amariglio N, Jacob-Hirsch J, Ben-Chetrit N, Tarcic G, Lindzen M, Avraham R, Liao YC, Trusk P, Lyass A, Rechavi G, Spector NL, Lo SH, Schmitt F, Bacus SS, Yarden Y. Katz M, et al. Among authors: yarden y. Nat Cell Biol. 2007 Aug;9(8):961-9. doi: 10.1038/ncb1622. Epub 2007 Jul 22. Nat Cell Biol. 2007. PMID: 17643115

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