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Evidence for a novel mechanism for gene amplification in multiple myeloma: 1q12 pericentromeric heterochromatin mediates breakage-fusion-bridge cycles of a 1q12 approximately 23 amplicon.
Sawyer JR, Tian E, Thomas E, Koller M, Stangeby C, Sammartino G, Goosen L, Swanson C, Binz RL, Barlogie B, Shaughnessy J. Sawyer JR, et al. Br J Haematol. 2009 Nov;147(4):484-94. doi: 10.1111/j.1365-2141.2009.07869.x. Epub 2009 Sep 9. Br J Haematol. 2009. PMID: 19744130 Free PMC article.
Prediction of cytogenetic abnormalities with gene expression profiles.
Zhou Y, Zhang Q, Stephens O, Heuck CJ, Tian E, Sawyer JR, Cartron-Mizeracki MA, Qu P, Keller J, Epstein J, Barlogie B, Shaughnessy JD Jr. Zhou Y, et al. Among authors: sawyer jr. Blood. 2012 May 24;119(21):e148-50. doi: 10.1182/blood-2011-10-388702. Epub 2012 Apr 10. Blood. 2012. PMID: 22496154 Free PMC article.
A validated gene expression model of high-risk multiple myeloma is defined by deregulated expression of genes mapping to chromosome 1.
Shaughnessy JD Jr, Zhan F, Burington BE, Huang Y, Colla S, Hanamura I, Stewart JP, Kordsmeier B, Randolph C, Williams DR, Xiao Y, Xu H, Epstein J, Anaissie E, Krishna SG, Cottler-Fox M, Hollmig K, Mohiuddin A, Pineda-Roman M, Tricot G, van Rhee F, Sawyer J, Alsayed Y, Walker R, Zangari M, Crowley J, Barlogie B. Shaughnessy JD Jr, et al. Among authors: sawyer j. Blood. 2007 Mar 15;109(6):2276-84. doi: 10.1182/blood-2006-07-038430. Epub 2006 Nov 14. Blood. 2007. PMID: 17105813 Free article.
312 results