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Real-time single-molecule electronic DNA sequencing by synthesis using polymer-tagged nucleotides on a nanopore array.
Fuller CW, Kumar S, Porel M, Chien M, Bibillo A, Stranges PB, Dorwart M, Tao C, Li Z, Guo W, Shi S, Korenblum D, Trans A, Aguirre A, Liu E, Harada ET, Pollard J, Bhat A, Cech C, Yang A, Arnold C, Palla M, Hovis J, Chen R, Morozova I, Kalachikov S, Russo JJ, Kasianowicz JJ, Davis R, Roever S, Church GM, Ju J. Fuller CW, et al. Proc Natl Acad Sci U S A. 2016 May 10;113(19):5233-8. doi: 10.1073/pnas.1601782113. Epub 2016 Apr 18. Proc Natl Acad Sci U S A. 2016. PMID: 27091962 Free PMC article.
Design and characterization of a nanopore-coupled polymerase for single-molecule DNA sequencing by synthesis on an electrode array.
Stranges PB, Palla M, Kalachikov S, Nivala J, Dorwart M, Trans A, Kumar S, Porel M, Chien M, Tao C, Morozova I, Li Z, Shi S, Aberra A, Arnold C, Yang A, Aguirre A, Harada ET, Korenblum D, Pollard J, Bhat A, Gremyachinskiy D, Bibillo A, Chen R, Davis R, Russo JJ, Fuller CW, Roever S, Ju J, Church GM. Stranges PB, et al. Among authors: fuller cw. Proc Natl Acad Sci U S A. 2016 Nov 1;113(44):E6749-E6756. doi: 10.1073/pnas.1608271113. Epub 2016 Oct 11. Proc Natl Acad Sci U S A. 2016. PMID: 27729524 Free PMC article.
Multiplex Single-Molecule Kinetics of Nanopore-Coupled Polymerases.
Palla M, Punthambaker S, Stranges B, Vigneault F, Nivala J, Wiegand D, Ayer A, Craig T, Gremyachinskiy D, Franklin H, Sun S, Pollard J, Trans A, Arnold C, Schwab C, Mcgaw C, Sarvabhowman P, Dalal D, Thai E, Amato E, Lederman I, Taing M, Kelley S, Qwan A, Fuller CW, Roever S, Church GM. Palla M, et al. Among authors: fuller cw. ACS Nano. 2021 Jan 26;15(1):489-502. doi: 10.1021/acsnano.0c05226. Epub 2020 Dec 28. ACS Nano. 2021. PMID: 33370106
Molecular electronics sensors on a scalable semiconductor chip: A platform for single-molecule measurement of binding kinetics and enzyme activity.
Fuller CW, Padayatti PS, Abderrahim H, Adamiak L, Alagar N, Ananthapadmanabhan N, Baek J, Chinni S, Choi C, Delaney KJ, Dubielzig R, Frkanec J, Garcia C, Gardner C, Gebhardt D, Geiser T, Gutierrez Z, Hall DA, Hodges AP, Hou G, Jain S, Jones T, Lobaton R, Majzik Z, Marte A, Mohan P, Mola P 2nd, Mudondo P, Mullinix J, Nguyen T, Ollinger F, Orr S, Ouyang Y, Pan P, Park N, Porras D, Prabhu K, Reese C, Ruel T, Sauerbrey T, Sawyer JR, Sinha P, Tu J, Venkatesh AG, VijayKumar S, Zheng L, Jin S, Tour JM, Church GM, Mola PW, Merriman B. Fuller CW, et al. Proc Natl Acad Sci U S A. 2022 Feb 1;119(5):e2112812119. doi: 10.1073/pnas.2112812119. Proc Natl Acad Sci U S A. 2022. PMID: 35074874 Free PMC article.
The challenges of sequencing by synthesis.
Fuller CW, Middendorf LR, Benner SA, Church GM, Harris T, Huang X, Jovanovich SB, Nelson JR, Schloss JA, Schwartz DC, Vezenov DV. Fuller CW, et al. Nat Biotechnol. 2009 Nov;27(11):1013-23. doi: 10.1038/nbt.1585. Epub 2009 Nov 6. Nat Biotechnol. 2009. PMID: 19898456 Review.
133 results