HIV protein Nef causes dyslipidemia and formation of foam cells in mouse models of atherosclerosis.
Cui HL, Ditiatkovski M, Kesani R, Bobryshev YV, Liu Y, Geyer M, Mukhamedova N, Bukrinsky M, Sviridov D.
Cui HL, et al. Among authors: bukrinsky m.
FASEB J. 2014 Jul;28(7):2828-39. doi: 10.1096/fj.13-246876. Epub 2014 Mar 18.
FASEB J. 2014.
PMID: 24642731
Free PMC article.
Taken together, our findings suggest that Nef causes dyslipidemia and accumulation of cholesterol in macrophages within the vessel wall, supporting the role of Nef in pathogenesis of atherosclerosis in HIV-infected patients.-Cui, H. L., Ditiatkovski, M., Kesani, R., Bobrys …
Taken together, our findings suggest that Nef causes dyslipidemia and accumulation of cholesterol in macrophages within the vessel wall, sup …