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A phase I study of perifosine with temsirolimus for recurrent pediatric solid tumors.
Becher OJ, Gilheeney SW, Khakoo Y, Lyden DC, Haque S, De Braganca KC, Kolesar JM, Huse JT, Modak S, Wexler LH, Kramer K, Spasojevic I, Dunkel IJ. Becher OJ, et al. Among authors: spasojevic i. Pediatr Blood Cancer. 2017 Jul;64(7). doi: 10.1002/pbc.26409. Epub 2016 Dec 30. Pediatr Blood Cancer. 2017. PMID: 28035748 Clinical Trial.
A high-throughput in vitro drug screen in a genetically engineered mouse model of diffuse intrinsic pontine glioma identifies BMS-754807 as a promising therapeutic agent.
Halvorson KG, Barton KL, Schroeder K, Misuraca KL, Hoeman C, Chung A, Crabtree DM, Cordero FJ, Singh R, Spasojevic I, Berlow N, Pal R, Becher OJ. Halvorson KG, et al. Among authors: spasojevic i. PLoS One. 2015 Mar 6;10(3):e0118926. doi: 10.1371/journal.pone.0118926. eCollection 2015. PLoS One. 2015. PMID: 25748921 Free PMC article.
A phase I study of single-agent perifosine for recurrent or refractory pediatric CNS and solid tumors.
Becher OJ, Millard NE, Modak S, Kushner BH, Haque S, Spasojevic I, Trippett TM, Gilheeney SW, Khakoo Y, Lyden DC, De Braganca KC, Kolesar JM, Huse JT, Kramer K, Cheung NV, Dunkel IJ. Becher OJ, et al. Among authors: spasojevic i. PLoS One. 2017 Jun 5;12(6):e0178593. doi: 10.1371/journal.pone.0178593. eCollection 2017. PLoS One. 2017. PMID: 28582410 Free PMC article. Clinical Trial.
Treatment with imatinib improves drug delivery and efficacy in NSCLC xenografts.
Vlahovic G, Ponce AM, Rabbani Z, Salahuddin FK, Zgonjanin L, Spasojevic I, Vujaskovic Z, Dewhirst MW. Vlahovic G, et al. Among authors: spasojevic i. Br J Cancer. 2007 Sep 17;97(6):735-40. doi: 10.1038/sj.bjc.6603941. Epub 2007 Aug 21. Br J Cancer. 2007. PMID: 17712313 Free PMC article.
Potential for a novel manganese porphyrin compound as adjuvant canine lymphoma therapy.
Boss MK, Dewhirst MW, Sampaio RS, Bennett A, Tovmasyan A, Berman KG, Beaven AW, Rizzieri DA, Batinic-Haberle I, Hauck ML, Spasojevic I. Boss MK, et al. Among authors: spasojevic i. Cancer Chemother Pharmacol. 2017 Aug;80(2):421-431. doi: 10.1007/s00280-017-3372-z. Epub 2017 Jul 6. Cancer Chemother Pharmacol. 2017. PMID: 28685347 Free PMC article.
Interplay between ATRX and IDH1 mutations governs innate immune responses in diffuse gliomas.
Hariharan S, Whitfield BT, Pirozzi CJ, Waitkus MS, Brown MC, Bowie ML, Irvin DM, Roso K, Fuller R, Hostettler J, Dharmaiah S, Gibson EA, Briley A, Mangoli A, Fraley C, Shobande M, Stevenson K, Zhang G, Malgulwar PB, Roberts H, Roskoski M, Spasojevic I, Keir ST, He Y, Castro MG, Huse JT, Ashley DM. Hariharan S, et al. Among authors: spasojevic i. Nat Commun. 2024 Jan 25;15(1):730. doi: 10.1038/s41467-024-44932-w. Nat Commun. 2024. PMID: 38272925 Free PMC article.
246 results