Zhou L - Search Results

1

Tau association with synaptic vesicles causes presynaptic dysfunction.

Zhou L, McInnes J, Wierda K, Holt M, Herrmann AG, Jackson RJ, Wang YC, Swerts J, Beyens J, Miskiewicz K, Vilain S, Dewachter I, Moechars D, De Strooper B, Spires-Jones TL, De Wit J, Verstreken P. Zhou L, et al. Nat Commun. 2017 May 11;8:15295. doi: 10.1038/ncomms15295. Nat Commun. 2017. PMID: 28492240 Free PMC article.

2

Inhibition of beta-secretase in vivo via antibody binding to unique loops (D and F) of BACE1.

Zhou L, Chávez-Gutiérrez L, Bockstael K, Sannerud R, Annaert W, May PC, Karran E, De Strooper B. Zhou L, et al. J Biol Chem. 2011 Mar 11;286(10):8677-8687. doi: 10.1074/jbc.M110.194860. Epub 2011 Jan 5. J Biol Chem. 2011. PMID: 21209097 Free PMC article.

3

Amyloid precursor protein mutation E682K at the alternative β-secretase cleavage β'-site increases Aβ generation.

Zhou L, Brouwers N, Benilova I, Vandersteen A, Mercken M, Van Laere K, Van Damme P, Demedts D, Van Leuven F, Sleegers K, Broersen K, Van Broeckhoven C, Vandenberghe R, De Strooper B. Zhou L, et al. EMBO Mol Med. 2011 May;3(5):291-302. doi: 10.1002/emmm.201100138. Epub 2011 Apr 15. EMBO Mol Med. 2011. PMID: 21500352 Free PMC article.

4

The mechanism of γ-Secretase dysfunction in familial Alzheimer disease.

Chávez-Gutiérrez L, Bammens L, Benilova I, Vandersteen A, Benurwar M, Borgers M, Lismont S, Zhou L, Van Cleynenbreugel S, Esselmann H, Wiltfang J, Serneels L, Karran E, Gijsen H, Schymkowitz J, Rousseau F, Broersen K, De Strooper B. Chávez-Gutiérrez L, et al. Among authors: zhou l. EMBO J. 2012 May 16;31(10):2261-74. doi: 10.1038/emboj.2012.79. Epub 2012 Apr 13. EMBO J. 2012. PMID: 22505025 Free PMC article.

5

The neural cell adhesion molecules L1 and CHL1 are cleaved by BACE1 protease in vivo.

Zhou L, Barão S, Laga M, Bockstael K, Borgers M, Gijsen H, Annaert W, Moechars D, Mercken M, Gevaert K, De Strooper B. Zhou L, et al. J Biol Chem. 2012 Jul 27;287(31):25927-40. doi: 10.1074/jbc.M112.377465. Epub 2012 Jun 12. J Biol Chem. 2012. PMID: 22692213 Free PMC article.

6

BACE1 levels correlate with phospho-tau levels in human cerebrospinal fluid.

Barao S, Zhou L, Adamczuk K, Vanhoutvin T, van Leuven F, Demedts D, Vijverman AC, Bossuyt X, Vandenberghe R, De Strooper B. Barao S, et al. Among authors: zhou l. Curr Alzheimer Res. 2013 Sep;10(7):671-8. doi: 10.2174/15672050113109990138. Curr Alzheimer Res. 2013. PMID: 23566348

7

Ultrafast synaptic endocytosis cycles to the center stage.

Zhou L, McInnes J, Verstreken P. Zhou L, et al. Dev Cell. 2014 Jan 13;28(1):5-6. doi: 10.1016/j.devcel.2013.12.017. Dev Cell. 2014. PMID: 24434135 Free article.

8

Fast and efficient Drosophila melanogaster gene knock-ins using MiMIC transposons.

Vilain S, Vanhauwaert R, Maes I, Schoovaerts N, Zhou L, Soukup S, da Cunha R, Lauwers E, Fiers M, Verstreken P. Vilain S, et al. Among authors: zhou l. G3 (Bethesda). 2014 Oct 8;4(12):2381-7. doi: 10.1534/g3.114.014803. G3 (Bethesda). 2014. PMID: 25298537 Free PMC article.

9

Antagonistic Effects of BACE1 and APH1B-γ-Secretase Control Axonal Guidance by Regulating Growth Cone Collapse.

Barão S, Gärtner A, Leyva-Díaz E, Demyanenko G, Munck S, Vanhoutvin T, Zhou L, Schachner M, López-Bendito G, Maness PF, De Strooper B. Barão S, et al. Among authors: zhou l. Cell Rep. 2015 Sep 1;12(9):1367-76. doi: 10.1016/j.celrep.2015.07.059. Epub 2015 Aug 20. Cell Rep. 2015. PMID: 26299962 Free PMC article.

10

Reprogramming neurodegeneration in the big data era.

Zhou L, Verstreken P. Zhou L, et al. Curr Opin Neurobiol. 2018 Feb;48:167-173. doi: 10.1016/j.conb.2017.12.015. Epub 2018 Jan 10. Curr Opin Neurobiol. 2018. PMID: 29331684 Review.

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