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Epigenetic Mechanisms of Gene Regulation in Amyotrophic Lateral Sclerosis.
Jimenez-Pacheco A, Franco JM, Lopez S, Gomez-Zumaquero JM, Magdalena Leal-Lasarte M, Caballero-Hernandez DE, Cejudo-Guillén M, Pozo D. Jimenez-Pacheco A, et al. Among authors: pozo d. Adv Exp Med Biol. 2017;978:255-275. doi: 10.1007/978-3-319-53889-1_14. Adv Exp Med Biol. 2017. PMID: 28523551 Review.
Chaperoned amyloid proteins for immune manipulation: α-Synuclein/Hsp70 shifts immunity toward a modulatory phenotype.
Labrador-Garrido A, Cejudo-Guillén M, Klippstein R, De Genst EJ, Tomas-Gallardo L, Leal MM, Villadiego J, Toledo-Aral JJ, Dobson CM, Pozo D, Roodveldt C. Labrador-Garrido A, et al. Among authors: pozo d. Immun Inflamm Dis. 2014 Dec;2(4):226-38. doi: 10.1002/iid3.39. Epub 2014 Dec 5. Immun Inflamm Dis. 2014. PMID: 25866630 Free PMC article.
The 'Omics' of Amyotrophic Lateral Sclerosis.
Caballero-Hernandez D, Toscano MG, Cejudo-Guillen M, Garcia-Martin ML, Lopez S, Franco JM, Quintana FJ, Roodveldt C, Pozo D. Caballero-Hernandez D, et al. Among authors: pozo d. Trends Mol Med. 2016 Jan;22(1):53-67. doi: 10.1016/j.molmed.2015.11.001. Epub 2015 Dec 13. Trends Mol Med. 2016. PMID: 26691296 Review.
Extracellular TDP-43 aggregates target MAPK/MAK/MRK overlapping kinase (MOK) and trigger caspase-3/IL-18 signaling in microglia.
Leal-Lasarte MM, Franco JM, Labrador-Garrido A, Pozo D, Roodveldt C. Leal-Lasarte MM, et al. Among authors: pozo d. FASEB J. 2017 Jul;31(7):2797-2816. doi: 10.1096/fj.201601163R. Epub 2017 Mar 23. FASEB J. 2017. PMID: 28336525
Our study provides new insight into the immune phenotype, mechanisms, and signaling pathways that operate in microglial neurotoxic activation in ALS.-Leal-Lasarte, M. M., Franco, J. M., Labrador-Garrido, A., Pozo, D., Roodveldt, C. Extracellular TDP-43 aggregates ta …
Our study provides new insight into the immune phenotype, mechanisms, and signaling pathways that operate in microglial neurotoxic activatio …
138 results