Schwabe JWR - Search Results

1

In vitro evolution predicts emerging SARS-CoV-2 mutations with high affinity for ACE2 and cross-species binding.

Bate N, Savva CG, Moody PCE, Brown EA, Evans SE, Ball JK, Schwabe JWR, Sale JE, Brindle NPJ. Bate N, et al. Among authors: schwabe jwr. PLoS Pathog. 2022 Jul 18;18(7):e1010733. doi: 10.1371/journal.ppat.1010733. eCollection 2022 Jul. PLoS Pathog. 2022. PMID: 35849637 Free PMC article.

2

The ansamycin antibiotic, rifamycin SV, inhibits BCL6 transcriptional repression and forms a complex with the BCL6-BTB/POZ domain.

Evans SE, Goult BT, Fairall L, Jamieson AG, Ko Ferrigno P, Ford R, Schwabe JW, Wagner SD. Evans SE, et al. PLoS One. 2014 Mar 4;9(3):e90889. doi: 10.1371/journal.pone.0090889. eCollection 2014. PLoS One. 2014. PMID: 24595451 Free PMC article.

3

Backbone resonance assignment of the BCL6-BTB/POZ domain.

Lin LY, Evans SE, Fairall L, Schwabe JWR, Wagner SD, Muskett FW. Lin LY, et al. Among authors: schwabe jwr. Biomol NMR Assign. 2018 Apr;12(1):47-50. doi: 10.1007/s12104-017-9778-z. Epub 2017 Sep 19. Biomol NMR Assign. 2018. PMID: 28929458 Free PMC article.

4

Heme binding to human CLOCK affects interactions with the E-box.

Freeman SL, Kwon H, Portolano N, Parkin G, Venkatraman Girija U, Basran J, Fielding AJ, Fairall L, Svistunenko DA, Moody PCE, Schwabe JWR, Kyriacou CP, Raven EL. Freeman SL, et al. Among authors: schwabe jwr. Proc Natl Acad Sci U S A. 2019 Oct 1;116(40):19911-19916. doi: 10.1073/pnas.1905216116. Epub 2019 Sep 16. Proc Natl Acad Sci U S A. 2019. PMID: 31527239 Free PMC article.

5

Mechanism of Crosstalk between the LSD1 Demethylase and HDAC1 Deacetylase in the CoREST Complex.

Song Y, Dagil L, Fairall L, Robertson N, Wu M, Ragan TJ, Savva CG, Saleh A, Morone N, Kunze MBA, Jamieson AG, Cole PA, Hansen DF, Schwabe JWR. Song Y, et al. Among authors: schwabe jwr. Cell Rep. 2020 Feb 25;30(8):2699-2711.e8. doi: 10.1016/j.celrep.2020.01.091. Cell Rep. 2020. PMID: 32101746 Free PMC article.

6

The MiDAC histone deacetylase complex is essential for embryonic development and has a unique multivalent structure.

Turnbull RE, Fairall L, Saleh A, Kelsall E, Morris KL, Ragan TJ, Savva CG, Chandru A, Millard CJ, Makarova OV, Smith CJ, Roseman AM, Fry AM, Cowley SM, Schwabe JWR. Turnbull RE, et al. Among authors: schwabe jwr. Nat Commun. 2020 Jun 26;11(1):3252. doi: 10.1038/s41467-020-17078-8. Nat Commun. 2020. PMID: 32591534 Free PMC article.

7

The topology of chromatin-binding domains in the NuRD deacetylase complex.

Millard CJ, Fairall L, Ragan TJ, Savva CG, Schwabe JWR. Millard CJ, et al. Among authors: schwabe jwr. Nucleic Acids Res. 2020 Dec 16;48(22):12972-12982. doi: 10.1093/nar/gkaa1121. Nucleic Acids Res. 2020. PMID: 33264408 Free PMC article.

8

Histone H2B Deacylation Selectivity: Exploring Chromatin's Dark Matter with an Engineered Sortase.

Wang ZA, Whedon SD, Wu M, Wang S, Brown EA, Anmangandla A, Regan L, Lee K, Du J, Hong JY, Fairall L, Kay T, Lin H, Zhao Y, Schwabe JWR, Cole PA. Wang ZA, et al. Among authors: schwabe jwr. J Am Chem Soc. 2022 Mar 2;144(8):3360-3364. doi: 10.1021/jacs.1c13555. Epub 2022 Feb 17. J Am Chem Soc. 2022. PMID: 35175758 Free PMC article.

9

Hydroxamic Acid-Modified Peptide Library Provides Insights into the Molecular Basis for the Substrate Selectivity of HDAC Corepressor Complexes.

Archibald LJ, Brown EA, Millard CJ, Watson PJ, Robertson NS, Wang S, Schwabe JWR, Jamieson AG. Archibald LJ, et al. Among authors: schwabe jwr. ACS Chem Biol. 2022 Sep 16;17(9):2572-2582. doi: 10.1021/acschembio.2c00510. Epub 2022 Aug 16. ACS Chem Biol. 2022. PMID: 35973051 Free PMC article.

10

The oestrogen receptor recognizes an imperfectly palindromic response element through an alternative side-chain conformation.

Schwabe JW, Chapman L, Rhodes D. Schwabe JW, et al. Structure. 1995 Feb 15;3(2):201-13. doi: 10.1016/s0969-2126(01)00150-2. Structure. 1995. PMID: 7735836 Free article.

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