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Unsupervised representation learning improves genomic discovery and risk prediction for respiratory and circulatory functions and diseases.
Yun T, Cosentino J, Behsaz B, McCaw ZR, Hill D, Luben R, Lai D, Bates J, Yang H, Schwantes-An TH, Zhou Y, Khawaja AP, Carroll A, Hobbs BD, Cho MH, McLean CY, Hormozdiari F. Yun T, et al. Among authors: hobbs bd. medRxiv [Preprint]. 2023 Aug 29:2023.04.28.23289285. doi: 10.1101/2023.04.28.23289285. medRxiv. 2023. PMID: 37163049 Free PMC article. Preprint.
Identifying COPD subtypes using multi-trait genetics.
Ziyatdinov A, Hobbs BD, Kanaan-Izquierdo S, Moll M, Sakornsakolpat P, Shrine N, Chen J, Song K, Bowler RP, Castaldi PJ, Tobin MD, Kraft P, Silverman EK, Julienne H, Aschard H, Cho MH. Ziyatdinov A, et al. Among authors: hobbs bd. medRxiv [Preprint]. 2023 Feb 21:2023.02.20.23286186. doi: 10.1101/2023.02.20.23286186. medRxiv. 2023. PMID: 36865145 Free PMC article. Preprint.
Clinical Features of Genetic Resilience in Chronic Obstructive Pulmonary Disease.
Ghosh AJ, Moll M, Hess J, Hobbs BD, Love A, Coyne L, Cho MH, Castaldi P, Middleton FA, Perl A, Silverman EK, Hersh CP, Glatt SJ. Ghosh AJ, et al. Among authors: hobbs bd. medRxiv [Preprint]. 2023 Mar 7:2023.03.06.23286843. doi: 10.1101/2023.03.06.23286843. medRxiv. 2023. PMID: 36945553 Free PMC article. Preprint.
Combined Forced Expiratory Volume in 1 Second and Forced Vital Capacity Bronchodilator Response, Exacerbations, and Mortality in Chronic Obstructive Pulmonary Disease.
Fortis S, Comellas A, Make BJ, Hersh CP, Bodduluri S, Georgopoulos D, Kim V, Criner GJ, Dransfield MT, Bhatt SP; COPDGene Investigators–Core Units: <italic>Administrative Center</italic>, COPDGene Investigators–Clinical Centers: <italic>Ann Arbor VA</italic>. Fortis S, et al. Ann Am Thorac Soc. 2019 Jul;16(7):826-835. doi: 10.1513/AnnalsATS.201809-601OC. Ann Am Thorac Soc. 2019. PMID: 30908927 Free PMC article.
Polygenic and transcriptional risk scores identify chronic obstructive pulmonary disease subtypes.
Moll M, Hecker J, Platig J, Zhang J, Ghosh AJ, Pratte KA, Wang RS, Hill D, Konigsberg IR, Chiles JW, Hersh CP, Castaldi PJ, Glass K, Dy JG, Sin DD, Tal-Singer R, Mouded M, Rennard SI, Anderson GP, Kinney GL, Bowler RP, Curtis JL, McDonald ML, Silverman EK, Hobbs BD, Cho MH. Moll M, et al. Among authors: hobbs bd. medRxiv [Preprint]. 2024 May 20:2024.05.20.24307621. doi: 10.1101/2024.05.20.24307621. medRxiv. 2024. PMID: 38826461 Free PMC article. Preprint.
122 results