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Genomics and response to long-term oxygen therapy in chronic obstructive pulmonary disease.
Seo M, Qiu W, Bailey W, Criner GJ, Dransfield MT, Fuhlbrigge AL, Reilly JJ, Scholand MB, Castaldi P, Chase R, Parker M, Saferali A, Yun JH, Crapo JD, Cho MH, Beaty TH, Silverman EK, Hersh CP. Seo M, et al. Among authors: saferali a. J Mol Med (Berl). 2018 Dec;96(12):1375-1385. doi: 10.1007/s00109-018-1708-8. Epub 2018 Oct 23. J Mol Med (Berl). 2018. PMID: 30353303 Free PMC article. Clinical Trial.
Analysis of genetically driven alternative splicing identifies FBXO38 as a novel COPD susceptibility gene.
Saferali A, Yun JH, Parker MM, Sakornsakolpat P, Chase RP, Lamb A, Hobbs BD, Boezen MH, Dai X, de Jong K, Beaty TH, Wei W, Zhou X, Silverman EK, Cho MH, Castaldi PJ, Hersh CP; COPDGene Investigators; International COPD Genetics Consortium Investigators. Saferali A, et al. PLoS Genet. 2019 Jul 3;15(7):e1008229. doi: 10.1371/journal.pgen.1008229. eCollection 2019 Jul. PLoS Genet. 2019. PMID: 31269066 Free PMC article.
C FTR variants are associated with chronic bronchitis in smokers.
Saferali A, Qiao D, Kim W, Raraigh K, Levy H, Diaz AA, Cutting GR, Cho MH, Hersh CP; NHLBI TransOmics in Precision Medicine (TOPMed). Saferali A, et al. Eur Respir J. 2022 Aug 10;60(2):2101994. doi: 10.1183/13993003.01994-2021. Print 2022 Aug. Eur Respir J. 2022. PMID: 34996830 Free PMC article.
Lung tissue shows divergent gene expression between chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis.
Ghosh AJ, Hobbs BD, Yun JH, Saferali A, Moll M, Xu Z, Chase RP, Morrow J, Ziniti J, Sciurba F, Barwick L, Limper AH, Flaherty K, Criner G, Brown KK, Wise R, Martinez FJ, McGoldrick D, Cho MH, DeMeo DL, Silverman EK, Castaldi PJ; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium; Hersh CP. Ghosh AJ, et al. Among authors: saferali a. Respir Res. 2022 Apr 21;23(1):97. doi: 10.1186/s12931-022-02013-w. Respir Res. 2022. PMID: 35449067 Free PMC article.
Blood Gene Expression and Immune Cell Subtypes Associated with Chronic Obstructive Pulmonary Disease Exacerbations.
Ryu MH, Yun JH, Morrow JD, Saferali A, Castaldi P, Chase R, Stav M, Xu Z, Barjaktarevic I, Han M, Labaki W, Huang YJ, Christenson S, O'Neal W, Bowler R, Sin DD, Freeman CM, Curtis JL, Hersh CP. Ryu MH, et al. Among authors: saferali a. Am J Respir Crit Care Med. 2023 Aug 1;208(3):247-255. doi: 10.1164/rccm.202301-0085OC. Am J Respir Crit Care Med. 2023. PMID: 37286295
46 results