Schoen WR - Search Results

1

A potent, orally bioavailable benzazepinone growth hormone secretagogue.

DeVita RJ, Bochis R, Frontier AJ, Kotliar A, Fisher MH, Schoen WR, Wyvratt MJ, Cheng K, Chan WW, Butler B, Jacks TM, Hickey GJ, Schleim KD, Leung K, Chen Z, Chiu SL, Feeney WP, Cunningham PK, Smith RG. DeVita RJ, et al. Among authors: schoen wr. J Med Chem. 1998 May 7;41(10):1716-28. doi: 10.1021/jm970816j. J Med Chem. 1998. PMID: 9572898

2

A novel 3-substituted benzazepinone growth hormone secretagogue (L-692,429).

Schoen WR, Pisano JM, Prendergast K, Wyvratt MJ Jr, Fisher MH, Cheng K, Chan WW, Butler B, Smith RG, Ball RG. Schoen WR, et al. J Med Chem. 1994 Apr 1;37(7):897-906. doi: 10.1021/jm00033a006. J Med Chem. 1994. PMID: 8151616

3

Efficacy and specificity of L-692,429, a novel nonpeptidyl growth hormone secretagogue, in beagles.

Hickey G, Jacks T, Judith F, Taylor J, Schoen WR, Krupa D, Cunningham P, Clark J, Smith RG. Hickey G, et al. Among authors: schoen wr. Endocrinology. 1994 Feb;134(2):695-701. doi: 10.1210/endo.134.2.8299565. Endocrinology. 1994. PMID: 8299565

4

Stimulation of growth hormone release from rat primary pituitary cells by L-692,429, a novel non-peptidyl GH secretagogue.

Cheng K, Chan WW, Butler B, Wei L, Schoen WR, Wyvratt MJ Jr, Fisher MH, Smith RG. Cheng K, et al. Among authors: schoen wr. Endocrinology. 1993 Jun;132(6):2729-31. doi: 10.1210/endo.132.6.8389289. Endocrinology. 1993. PMID: 8389289

5

A nonpeptidyl growth hormone secretagogue.

Smith RG, Cheng K, Schoen WR, Pong SS, Hickey G, Jacks T, Butler B, Chan WW, Chaung LY, Judith F, et al. Smith RG, et al. Among authors: schoen wr. Science. 1993 Jun 11;260(5114):1640-3. doi: 10.1126/science.8503009. Science. 1993. PMID: 8503009

6

Acyclic structural variants of growth hormone secretagogue L-692,429.

Lin P, Pisano JM, Schoen WR, Cheng K, Chan WW, Butler BS, Smith RG, Fisher MH, Wyvratt MJ. Lin P, et al. Among authors: schoen wr. Bioorg Med Chem Lett. 1999 Nov 15;9(22):3237-42. doi: 10.1016/s0960-894x(99)00568-5. Bioorg Med Chem Lett. 1999. PMID: 10576695

7

Effects of acute and repeated intravenous administration of L-692,585, a novel non-peptidyl growth hormone secretagogue, on plasma growth hormone, IGF-1, ACTH, cortisol, prolactin, insulin, and thyroxine levels in beagles.

Jacks T, Hickey G, Judith F, Taylor J, Chen H, Krupa D, Feeney W, Schoen W, Ok D, Fisher M, et al. Jacks T, et al. J Endocrinol. 1994 Nov;143(2):399-406. doi: 10.1677/joe.0.1430399. J Endocrinol. 1994. PMID: 7830002

8

Phosphinic acid inhibitors of D-alanyl-D-alanine ligase.

Parsons WH, Patchett AA, Bull HG, Schoen WR, Taub D, Davidson J, Combs PL, Springer JP, Gadebusch H, Weissberger B, et al. Parsons WH, et al. Among authors: schoen wr. J Med Chem. 1988 Sep;31(9):1772-8. doi: 10.1021/jm00117a017. J Med Chem. 1988. PMID: 3137344

9

Optimization of the 4-aryl group of 4-aryl-pyridine glucagon antagonists: development of an efficient, alternative synthesis.

Smith RA, Hertzog DL, Osterhout MH, Ladouceur GH, Korpusik M, Bobko MA, Jones JH, Phelan K, Romero RH, Hundertmark T, MacDougall ML, Livingston JN, Schoen WR. Smith RA, et al. Among authors: schoen wr. Bioorg Med Chem Lett. 2002 May 6;12(9):1303-6. doi: 10.1016/s0960-894x(02)00143-9. Bioorg Med Chem Lett. 2002. PMID: 11965376

10

Integration of optimized substituent patterns to produce highly potent 4-aryl-pyridine glucagon receptor antagonists.

Ladouceur GH, Cook JH, Hertzog DL, Jones JH, Hundertmark T, Korpusik M, Lease TG, Livingston JN, MacDougall ML, Osterhout MH, Phelan K, Romero RH, Schoen WR, Shao C, Smith RA. Ladouceur GH, et al. Among authors: schoen wr. Bioorg Med Chem Lett. 2002 Dec 2;12(23):3421-4. doi: 10.1016/s0960-894x(02)00736-9. Bioorg Med Chem Lett. 2002. PMID: 12419375

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