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Page 1
A potent, orally bioavailable benzazepinone growth hormone secretagogue.
DeVita RJ, Bochis R, Frontier AJ, Kotliar A, Fisher MH, Schoen WR, Wyvratt MJ, Cheng K, Chan WW, Butler B, Jacks TM, Hickey GJ, Schleim KD, Leung K, Chen Z, Chiu SL, Feeney WP, Cunningham PK, Smith RG. DeVita RJ, et al. Among authors: wyvratt mj. J Med Chem. 1998 May 7;41(10):1716-28. doi: 10.1021/jm970816j. J Med Chem. 1998. PMID: 9572898
Orally active growth hormone secretagogues.
Patchett AA, Smith RG, Wyvratt MJ. Patchett AA, et al. Among authors: wyvratt mj. Pharm Biotechnol. 1998;11:525-54. doi: 10.1007/0-306-47384-4_23. Pharm Biotechnol. 1998. PMID: 9760695 Review. No abstract available.
L-770,644: a potent and selective human beta3 adrenergic receptor agonist with improved oral bioavailability.
Shih TL, Candelore MR, Cascieri MA, Chiu SH, Colwell LF Jr, Deng L, Feeney WP, Forrest MJ, Hom GJ, MacIntyre DE, Miller RR, Stearns RA, Strader CD, Tota L, Wyvratt MJ, Fisher MH, Weber AE. Shih TL, et al. Among authors: wyvratt mj. Bioorg Med Chem Lett. 1999 May 3;9(9):1251-4. doi: 10.1016/s0960-894x(99)00182-1. Bioorg Med Chem Lett. 1999. PMID: 10340609
Acyclic structural variants of growth hormone secretagogue L-692,429.
Lin P, Pisano JM, Schoen WR, Cheng K, Chan WW, Butler BS, Smith RG, Fisher MH, Wyvratt MJ. Lin P, et al. Among authors: wyvratt mj. Bioorg Med Chem Lett. 1999 Nov 15;9(22):3237-42. doi: 10.1016/s0960-894x(99)00568-5. Bioorg Med Chem Lett. 1999. PMID: 10576695
Discovery of an orally bioavailable alkyl oxadiazole beta3 adrenergic receptor agonist.
Feng DD, Biftu T, Candelore MR, Cascieri MA, Colwell LF Jr, Deng L, Feeney WP, Forrest MJ, Hom GJ, MacIntyre DE, Miller RR, Stearns RA, Strader CD, Tota L, Wyvratt MJ, Fisher MH, Weber AE. Feng DD, et al. Among authors: wyvratt mj. Bioorg Med Chem Lett. 2000 Jul 3;10(13):1427-9. doi: 10.1016/s0960-894x(00)00267-5. Bioorg Med Chem Lett. 2000. PMID: 10888324
Substituted oxazole benzenesulfonamides as potent human beta3 adrenergic receptor agonists.
Ok HO, Reigle LB, Candelore MR, Cascieri MA, Colwell LF, Deng L, Feeney WP, Forrest MJ, Hom GJ, MacIntyre DE, Strader CD, Tota L, Wang P, Wyvratt MJ, Fisher MH, Weber AE. Ok HO, et al. Among authors: wyvratt mj. Bioorg Med Chem Lett. 2000 Jul 17;10(14):1531-4. doi: 10.1016/s0960-894x(00)00277-8. Bioorg Med Chem Lett. 2000. PMID: 10915043
82 results