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Rapid emergence of transcriptional heterogeneity upon molecular stress predisposes cells to two distinct states of senescence.
Geroscience. 2023 Apr;45(2):1115-1130. doi: 10.1007/s11357-022-00709-x. Epub 2022 Dec 23.
Geroscience. 2023.
PMID: 36562924
Free PMC article.
Chaperone biomarkers of lifespan and penetrance track the dosages of many other proteins.
Burnaevskiy N, Sands B, Yun S, Tedesco PM, Johnson TE, Kaeberlein M, Brent R, Mendenhall A.
Burnaevskiy N, et al.
Nat Commun. 2019 Dec 16;10(1):5725. doi: 10.1038/s41467-019-13664-7.
Nat Commun. 2019.
PMID: 31844058
Free PMC article.
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Cell-to-Cell Variation in Gene Expression for Cultured Human Cells Is Controlled in Trans by Diverse Genes: Implications for the Pathobiology of Aging.
Zhang J, Burnaevskiy N, Annis J, Han W, Hou D, Ladd P, Lee L, Mendenhall AR, Oshima J, Martin GM.
Zhang J, et al.
J Gerontol A Biol Sci Med Sci. 2020 Nov 13;75(12):2295-2298. doi: 10.1093/gerona/glaa027.
J Gerontol A Biol Sci Med Sci. 2020.
PMID: 31957802
Free PMC article.
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