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Inherent and benzo[a]pyrene-induced differential aryl hydrocarbon receptor signaling greatly affects life span, atherosclerosis, cardiac gene expression, and body and heart growth in mice.
Kerley-Hamilton JS, Trask HW, Ridley CJ, Dufour E, Lesseur C, Ringelberg CS, Moodie KL, Shipman SL, Korc M, Gui J, Shworak NW, Tomlinson CR. Kerley-Hamilton JS, et al. Toxicol Sci. 2012 Apr;126(2):391-404. doi: 10.1093/toxsci/kfs002. Epub 2012 Jan 6. Toxicol Sci. 2012. PMID: 22228805 Free PMC article.