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Impaired dynamics and function of mitochondria caused by mtDNA toxicity leads to heart failure.
Lauritzen KH, Kleppa L, Aronsen JM, Eide L, Carlsen H, Haugen ØP, Sjaastad I, Klungland A, Rasmussen LJ, Attramadal H, Storm-Mathisen J, Bergersen LH. Lauritzen KH, et al. Among authors: bergersen lh. Am J Physiol Heart Circ Physiol. 2015 Aug 1;309(3):H434-49. doi: 10.1152/ajpheart.00253.2014. Epub 2015 Jun 8. Am J Physiol Heart Circ Physiol. 2015. PMID: 26055793 Free article.
Initial brain aging: heterogeneity of mitochondrial size is associated with decline in complex I-linked respiration in cortex and hippocampus.
Thomsen K, Yokota T, Hasan-Olive MM, Sherazi N, Fakouri NB, Desler C, Regnell CE, Larsen S, Rasmussen LJ, Dela F, Bergersen LH, Lauritzen M. Thomsen K, et al. Among authors: bergersen lh. Neurobiol Aging. 2018 Jan;61:215-224. doi: 10.1016/j.neurobiolaging.2017.08.004. Epub 2017 Aug 12. Neurobiol Aging. 2018. PMID: 29031832
102 results