Bern M - Search Results

1

Fc Engineering of Human IgG1 for Altered Binding to the Neonatal Fc Receptor Affects Fc Effector Functions.

Grevys A, Bern M, Foss S, Bratlie DB, Moen A, Gunnarsen KS, Aase A, Michaelsen TE, Sandlie I, Andersen JT. Grevys A, et al. Among authors: bern m. J Immunol. 2015 Jun 1;194(11):5497-508. doi: 10.4049/jimmunol.1401218. Epub 2015 Apr 22. J Immunol. 2015. PMID: 25904551 Free PMC article.

2

Dissection of the neonatal Fc receptor (FcRn)-albumin interface using mutagenesis and anti-FcRn albumin-blocking antibodies.

Sand KM, Dalhus B, Christianson GJ, Bern M, Foss S, Cameron J, Sleep D, Bjørås M, Roopenian DC, Sandlie I, Andersen JT. Sand KM, et al. Among authors: bern m. J Biol Chem. 2014 Jun 13;289(24):17228-39. doi: 10.1074/jbc.M113.522565. Epub 2014 Apr 24. J Biol Chem. 2014. PMID: 24764301 Free PMC article.

3

Interaction with both domain I and III of albumin is required for optimal pH-dependent binding to the neonatal Fc receptor (FcRn).

Sand KM, Bern M, Nilsen J, Dalhus B, Gunnarsen KS, Cameron J, Grevys A, Bunting K, Sandlie I, Andersen JT. Sand KM, et al. Among authors: bern m. J Biol Chem. 2014 Dec 12;289(50):34583-94. doi: 10.1074/jbc.M114.587675. Epub 2014 Oct 24. J Biol Chem. 2014. PMID: 25344603 Free PMC article.

4

Unraveling the Interaction between FcRn and Albumin: Opportunities for Design of Albumin-Based Therapeutics.

Sand KM, Bern M, Nilsen J, Noordzij HT, Sandlie I, Andersen JT. Sand KM, et al. Among authors: bern m. Front Immunol. 2015 Jan 26;5:682. doi: 10.3389/fimmu.2014.00682. eCollection 2014. Front Immunol. 2015. PMID: 25674083 Free PMC article. Review.

5

The role of albumin receptors in regulation of albumin homeostasis: Implications for drug delivery.

Bern M, Sand KM, Nilsen J, Sandlie I, Andersen JT. Bern M, et al. J Control Release. 2015 Aug 10;211:144-62. doi: 10.1016/j.jconrel.2015.06.006. Epub 2015 Jun 6. J Control Release. 2015. PMID: 26055641 Review.

6

Enhanced FcRn-dependent transepithelial delivery of IgG by Fc-engineering and polymerization.

Foss S, Grevys A, Sand KMK, Bern M, Blundell P, Michaelsen TE, Pleass RJ, Sandlie I, Andersen JT. Foss S, et al. Among authors: bern m. J Control Release. 2016 Feb 10;223:42-52. doi: 10.1016/j.jconrel.2015.12.033. Epub 2015 Dec 21. J Control Release. 2016. PMID: 26718855

7

TRIM21 Immune Signaling Is More Sensitive to Antibody Affinity Than Its Neutralization Activity.

Foss S, Watkinson RE, Grevys A, McAdam MB, Bern M, Høydahl LS, Dalhus B, Michaelsen TE, Sandlie I, James LC, Andersen JT. Foss S, et al. Among authors: bern m. J Immunol. 2016 Apr 15;196(8):3452-3459. doi: 10.4049/jimmunol.1502601. Epub 2016 Mar 9. J Immunol. 2016. PMID: 26962230 Free PMC article.

8

A human endothelial cell-based recycling assay for screening of FcRn targeted molecules.

Grevys A, Nilsen J, Sand KMK, Daba MB, Øynebråten I, Bern M, McAdam MB, Foss S, Schlothauer T, Michaelsen TE, Christianson GJ, Roopenian DC, Blumberg RS, Sandlie I, Andersen JT. Grevys A, et al. Among authors: bern m. Nat Commun. 2018 Feb 12;9(1):621. doi: 10.1038/s41467-018-03061-x. Nat Commun. 2018. PMID: 29434196 Free PMC article.

9

Human and mouse albumin bind their respective neonatal Fc receptors differently.

Nilsen J, Bern M, Sand KMK, Grevys A, Dalhus B, Sandlie I, Andersen JT. Nilsen J, et al. Among authors: bern m. Sci Rep. 2018 Oct 2;8(1):14648. doi: 10.1038/s41598-018-32817-0. Sci Rep. 2018. PMID: 30279529 Free PMC article.

10

An intact C-terminal end of albumin is required for its long half-life in humans.

Nilsen J, Trabjerg E, Grevys A, Azevedo C, Brennan SO, Stensland M, Wilson J, Sand KMK, Bern M, Dalhus B, Roopenian DC, Sandlie I, Rand KD, Andersen JT. Nilsen J, et al. Among authors: bern m. Commun Biol. 2020 Apr 20;3(1):181. doi: 10.1038/s42003-020-0903-7. Commun Biol. 2020. PMID: 32313072 Free PMC article.

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