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Page 1
Integrative approach identifies corticosteroid response variant in diverse populations with asthma.
Levin AM, Gui H, Hernandez-Pacheco N, Yang M, Xiao S, Yang JJ, Hochstadt S, Barczak AJ, Eckalbar WL, Rynkowski D, Samedy LA, Kwok PY, Pino-Yanes M, Erle DJ, Lanfear DE, Burchard EG, Williams LK. Levin AM, et al. J Allergy Clin Immunol. 2019 May;143(5):1791-1802. doi: 10.1016/j.jaci.2018.09.034. Epub 2018 Oct 24. J Allergy Clin Immunol. 2019. PMID: 30367910 Free PMC article.
Genome-wide association study of inhaled corticosteroid response in admixed children with asthma.
Hernandez-Pacheco N, Farzan N, Francis B, Karimi L, Repnik K, Vijverberg SJ, Soares P, Schieck M, Gorenjak M, Forno E, Eng C, Oh SS, Pérez-Méndez L, Berce V, Tavendale R, Samedy LA, Hunstman S, Hu D, Meade K, Farber HJ, Avila PC, Serebrisky D, Thyne SM, Brigino-Buenaventura E, Rodriguez-Cintron W, Sen S, Kumar R, Lenoir M, Rodriguez-Santana JR, Celedón JC, Mukhopadhyay S, Potočnik U, Pirmohamed M, Verhamme KM, Kabesch M, Palmer CNA, Hawcutt DB, Flores C, Maitland-van der Zee AH, Burchard EG, Pino-Yanes M. Hernandez-Pacheco N, et al. Clin Exp Allergy. 2019 Jun;49(6):789-798. doi: 10.1111/cea.13354. Epub 2019 Feb 15. Clin Exp Allergy. 2019. PMID: 30697902 Free PMC article. Clinical Trial.
ADRB2 haplotypes and asthma exacerbations in children and young adults: An individual participant data meta-analysis.
Karimi L, Vijverberg SJ, Engelkes M, Hernandez-Pacheco N, Farzan N, Soares P, Pino-Yanes M, Jorgensen AL, Eng C, Mukhopadhyay S, Schieck M, Kabesch M, Burchard EG, Chew FT, Sio YY, Potočnik U, Gorenjak M, Hawcutt DB, Palmer CN, Turner S, Janssens HM, Maitland-van der Zee AH, Verhamme KMC; PiCA and SysPharmPedia consortia. Karimi L, et al. Among authors: hernandez pacheco n. Clin Exp Allergy. 2021 Sep;51(9):1157-1171. doi: 10.1111/cea.13965. Epub 2021 Jul 20. Clin Exp Allergy. 2021. PMID: 34128573 Free PMC article.
Multiomics analysis identifies BIRC3 as a novel glucocorticoid response-associated gene.
Kan M, Diwadkar AR, Shuai H, Joo J, Wang AL, Ong MS, Sordillo JE, Iribarren C, Lu MX, Hernandez-Pacheco N, Perez-Garcia J, Gorenjak M, Potočnik U, Burchard EG, Pino-Yanes M, Wu AC, Himes BE. Kan M, et al. Among authors: hernandez pacheco n. J Allergy Clin Immunol. 2022 Jun;149(6):1981-1991. doi: 10.1016/j.jaci.2021.11.025. Epub 2021 Dec 28. J Allergy Clin Immunol. 2022. PMID: 34971648 Free PMC article.
17q21 variant increases the risk of exacerbations in asthmatic children despite inhaled corticosteroids use.
Farzan N, Vijverberg SJ, Hernandez-Pacheco N, Bel EHD, Berce V, Bønnelykke K, Bisgaard H, Burchard EG, Canino G, Celedón JC, Chew FT, Chiang WC, Cloutier MM, Forno E, Francis B, Hawcutt DB, Herrera-Luis E, Kabesch M, Karimi L, Melén E, Mukhopadhyay S, Merid SK, Palmer CN, Pino-Yanes M, Pirmohamed M, Potočnik U, Repnik K, Schieck M, Sevelsted A, Sio YY, Smyth RL, Soares P, Söderhäll C, Tantisira KG, Tavendale R, Tse SM, Turner S, Verhamme KM, Maitland-van der Zee AH. Farzan N, et al. Allergy. 2018 Oct;73(10):2083-2088. doi: 10.1111/all.13499. Epub 2018 Jul 9. Allergy. 2018. PMID: 29885281 Free PMC article.
Identification of a novel locus associated with skin colour in African-admixed populations.
Hernandez-Pacheco N, Flores C, Alonso S, Eng C, Mak AC, Hunstman S, Hu D, White MJ, Oh SS, Meade K, Farber HJ, Avila PC, Serebrisky D, Thyne SM, Brigino-Buenaventura E, Rodriguez-Cintron W, Sen S, Kumar R, Lenoir M, Rodriguez-Santana JR, Burchard EG, Pino-Yanes M. Hernandez-Pacheco N, et al. Sci Rep. 2017 Mar 16;7:44548. doi: 10.1038/srep44548. Sci Rep. 2017. PMID: 28300201 Free PMC article.
Role of genomics in asthma exacerbations.
Herrera-Luis E, Hernandez-Pacheco N, Vijverberg SJ, Flores C, Pino-Yanes M. Herrera-Luis E, et al. Curr Opin Pulm Med. 2019 Jan;25(1):101-112. doi: 10.1097/MCP.0000000000000533. Curr Opin Pulm Med. 2019. PMID: 30334825 Review.
Meta-analysis of GWA studies provides new insights on the genetic architecture of skin pigmentation in recently admixed populations.
Lona-Durazo F, Hernandez-Pacheco N, Fan S, Zhang T, Choi J, Kovacs MA, Loftus SK, Le P, Edwards M, Fortes-Lima CA, Eng C, Huntsman S, Hu D, Gómez-Cabezas EJ, Marín-Padrón LC, Grauholm J, Mors O, Burchard EG, Norton HL, Pavan WJ, Brown KM, Tishkoff S, Pino-Yanes M, Beleza S, Marcheco-Teruel B, Parra EJ. Lona-Durazo F, et al. BMC Genet. 2019 Jul 17;20(1):59. doi: 10.1186/s12863-019-0765-5. BMC Genet. 2019. PMID: 31315583 Free PMC article.
29 results