1 Academic Unit of Palliative Care, Leeds Institute of Health Sciences, University of Leeds, Leeds, West Yorkshire, UK Department of Palliative Medicine, University Hospital, Bonn, Germany Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway Department of Anesthesia, Intensive Care, Pain Therapy and Palliative Care, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy European Palliative Care Research Center NTNU, Trondheim, Norway Edinburgh Cancer Research UK Centre, University of Edinburgh, Edinburgh, UK.