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Genetic analysis in European ancestry individuals identifies 517 loci associated with liver enzymes.
Pazoki R, Vujkovic M, Elliott J, Evangelou E, Gill D, Ghanbari M, van der Most PJ, Pinto RC, Wielscher M, Farlik M, Zuber V, de Knegt RJ, Snieder H, Uitterlinden AG; Lifelines Cohort Study; Lynch JA, Jiang X, Said S, Kaplan DE, Lee KM, Serper M, Carr RM, Tsao PS, Atkinson SR, Dehghan A, Tzoulaki I, Ikram MA, Herzig KH, Järvelin MR, Alizadeh BZ, O'Donnell CJ, Saleheen D, Voight BF, Chang KM, Thursz MR, Elliott P; VA Million Veteran Program. Pazoki R, et al. Among authors: lee km. Nat Commun. 2021 May 10;12(1):2579. doi: 10.1038/s41467-021-22338-2. Nat Commun. 2021. PMID: 33972514 Free PMC article.
Genome-wide association study of peripheral artery disease in the Million Veteran Program.
Klarin D, Lynch J, Aragam K, Chaffin M, Assimes TL, Huang J, Lee KM, Shao Q, Huffman JE, Natarajan P, Arya S, Small A, Sun YV, Vujkovic M, Freiberg MS, Wang L, Chen J, Saleheen D, Lee JS, Miller DR, Reaven P, Alba PR, Patterson OV, DuVall SL, Boden WE, Beckman JA, Gaziano JM, Concato J, Rader DJ, Cho K, Chang KM, Wilson PWF, O'Donnell CJ, Kathiresan S; VA Million Veteran Program; Tsao PS, Damrauer SM. Klarin D, et al. Among authors: lee js, lee km. Nat Med. 2019 Aug;25(8):1274-1279. doi: 10.1038/s41591-019-0492-5. Epub 2019 Jul 8. Nat Med. 2019. PMID: 31285632 Free PMC article.
Association of APOL1 Risk Alleles With Cardiovascular Disease in Blacks in the Million Veteran Program.
Bick AG, Akwo E, Robinson-Cohen C, Lee K, Lynch J, Assimes TL, DuVall S, Edwards T, Fang H, Freiberg SM, Giri A, Huffman JE, Huang J, Hull L, Kember RL, Klarin D, Lee JS, Levin M, Miller DR, Natarajan P, Saleheen D, Shao Q, Sun YV, Tang H, Wilson O, Chang KM, Cho K, Concato J, Gaziano JM, Kathiresan S, O'Donnell CJ, Rader DJ, Tsao PS, Wilson PW, Hung AM, Damrauer SM; VA Million Veteran Program. Bick AG, et al. Among authors: lee js, lee k. Circulation. 2019 Sep 17;140(12):1031-1040. doi: 10.1161/CIRCULATIONAHA.118.036589. Epub 2019 Jul 24. Circulation. 2019. PMID: 31337231 Free PMC article.
Discovery of 318 new risk loci for type 2 diabetes and related vascular outcomes among 1.4 million participants in a multi-ancestry meta-analysis.
Vujkovic M, Keaton JM, Lynch JA, Miller DR, Zhou J, Tcheandjieu C, Huffman JE, Assimes TL, Lorenz K, Zhu X, Hilliard AT, Judy RL, Huang J, Lee KM, Klarin D, Pyarajan S, Danesh J, Melander O, Rasheed A, Mallick NH, Hameed S, Qureshi IH, Afzal MN, Malik U, Jalal A, Abbas S, Sheng X, Gao L, Kaestner KH, Susztak K, Sun YV, DuVall SL, Cho K, Lee JS, Gaziano JM, Phillips LS, Meigs JB, Reaven PD, Wilson PW, Edwards TL, Rader DJ, Damrauer SM, O'Donnell CJ, Tsao PS; HPAP Consortium; Regeneron Genetics Center; VA Million Veteran Program; Chang KM, Voight BF, Saleheen D. Vujkovic M, et al. Among authors: lee js, lee km. Nat Genet. 2020 Jul;52(7):680-691. doi: 10.1038/s41588-020-0637-y. Epub 2020 Jun 15. Nat Genet. 2020. PMID: 32541925 Free PMC article.
Genetic determinants of increased body mass index mediate the effect of smoking on increased risk for type 2 diabetes but not coronary artery disease.
Thom CS, Ding Z, Levin MG, Damrauer SM, Lee KM, Lynch J, Chang KM, Tsao PS, Cho K, Wilson PWF, Assimes TL, Sun YV, O'Donnell CJ; VA Million Veteran Program; Vujkovic M, Voight BF. Thom CS, et al. Among authors: lee km. Hum Mol Genet. 2020 Nov 25;29(19):3327-3337. doi: 10.1093/hmg/ddaa193. Hum Mol Genet. 2020. PMID: 32833022 Free PMC article.
Validating a non-invasive, ALT-based non-alcoholic fatty liver phenotype in the million veteran program.
Serper M, Vujkovic M, Kaplan DE, Carr RM, Lee KM, Shao Q, Miller DR, Reaven PD, Phillips LS, O'Donnell CJ, Meigs JB, Wilson PWF, Vickers-Smith R, Kranzler HR, Justice AC, Gaziano JM, Muralidhar S, Pyarajan S, DuVall SL, Assimes TL, Lee JS, Tsao PS, Rader DJ, Damrauer SM, Lynch JA, Saleheen D, Voight BF, Chang KM; VA Million Veteran Program. Serper M, et al. Among authors: lee js, lee km. PLoS One. 2020 Aug 25;15(8):e0237430. doi: 10.1371/journal.pone.0237430. eCollection 2020. PLoS One. 2020. PMID: 32841307 Free PMC article.
Association Between Genetic Variation in Blood Pressure and Increased Lifetime Risk of Peripheral Artery Disease.
Levin MG, Klarin D, Walker VM, Gill D, Lynch J, Hellwege JN, Keaton JM, Lee KM, Assimes TL, Natarajan P, Hung AM, Edwards TL, Rader DJ, Gaziano JM, Davies NM, Tsao PS, Chang KM, Voight BF, Damrauer SM; VA Million Veteran Program. Levin MG, et al. Among authors: lee km. Arterioscler Thromb Vasc Biol. 2021 Jun;41(6):2027-2034. doi: 10.1161/ATVBAHA.120.315482. Epub 2021 Apr 15. Arterioscler Thromb Vasc Biol. 2021. PMID: 33853351 Free PMC article.
IL10RB as a key regulator of COVID-19 host susceptibility and severity.
Voloudakis G, Hoffman G, Venkatesh S, Lee KM, Dobrindt K, Vicari JM, Zhang W, Beckmann ND, Jiang S, Hoagland D, Bian J, Gao L, Corvelo A, Cho K, Lee JS, Iyengar SK, Luoh SW, Akbarian S, Striker R, Assimes TL, Schadt EE, Merad M, tenOever BR, Charney AW; Mount Sinai COVID-19 Biobank; VA Million Veteran Program COVID-19 Science Initiative; Brennand KJ, Lynch JA, Fullard JF, Roussos P. Voloudakis G, et al. Among authors: lee js, lee km. medRxiv [Preprint]. 2021 Jun 2:2021.05.31.21254851. doi: 10.1101/2021.05.31.21254851. medRxiv. 2021. PMID: 34100031 Free PMC article. Updated. Preprint.
2,952 results