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Combined Loss of Tet1 and Tet2 Promotes B Cell, but Not Myeloid Malignancies, in Mice.
Zhao Z, Chen L, Dawlaty MM, Pan F, Weeks O, Zhou Y, Cao Z, Shi H, Wang J, Lin L, Chen S, Yuan W, Qin Z, Ni H, Nimer SD, Yang FC, Jaenisch R, Jin P, Xu M. Zhao Z, et al. Among authors: pan f. Cell Rep. 2015 Nov 24;13(8):1692-704. doi: 10.1016/j.celrep.2015.10.037. Epub 2015 Nov 12. Cell Rep. 2015. PMID: 26586431 Free PMC article.
Tet2 loss leads to hypermutagenicity in haematopoietic stem/progenitor cells.
Pan F, Wingo TS, Zhao Z, Gao R, Makishima H, Qu G, Lin L, Yu M, Ortega JR, Wang J, Nazha A, Chen L, Yao B, Liu C, Chen S, Weeks O, Ni H, Phillips BL, Huang S, Wang J, He C, Li GM, Radivoyevitch T, Aifantis I, Maciejewski JP, Yang FC, Jin P, Xu M. Pan F, et al. Nat Commun. 2017 Apr 25;8:15102. doi: 10.1038/ncomms15102. Nat Commun. 2017. PMID: 28440315 Free PMC article.
RNA-dependent chromatin targeting of TET2 for endogenous retrovirus control in pluripotent stem cells.
Guallar D, Bi X, Pardavila JA, Huang X, Saenz C, Shi X, Zhou H, Faiola F, Ding J, Haruehanroengra P, Yang F, Li D, Sanchez-Priego C, Saunders A, Pan F, Valdes VJ, Kelley K, Blanco MG, Chen L, Wang H, Sheng J, Xu M, Fidalgo M, Shen X, Wang J. Guallar D, et al. Among authors: pan f. Nat Genet. 2018 Mar;50(3):443-451. doi: 10.1038/s41588-018-0060-9. Epub 2018 Feb 26. Nat Genet. 2018. PMID: 29483655 Free PMC article.
Loss of Asxl1 leads to myelodysplastic syndrome-like disease in mice.
Wang J, Li Z, He Y, Pan F, Chen S, Rhodes S, Nguyen L, Yuan J, Jiang L, Yang X, Weeks O, Liu Z, Zhou J, Ni H, Cai CL, Xu M, Yang FC. Wang J, et al. Among authors: pan f. Blood. 2014 Jan 23;123(4):541-53. doi: 10.1182/blood-2013-05-500272. Epub 2013 Nov 19. Blood. 2014. PMID: 24255920 Free PMC article.
Consecutive epigenetically-active agent combinations act in ID1-RUNX3-TET2 and HOXA pathways for Flt3ITD+ve AML.
Sayar H, Liu Y, Gao R, Zaid MA, Cripe LD, Weisenbach J, Sargent KJ, Nassiri M, Li L, Konig H, Suvannasankha A, Pan F, Shanmugam R, Goswami C, Kapur R, Xu M, Boswell HS. Sayar H, et al. Among authors: pan f. Oncotarget. 2017 Dec 25;9(5):5703-5715. doi: 10.18632/oncotarget.23655. eCollection 2018 Jan 19. Oncotarget. 2017. PMID: 29464028 Free PMC article.
2,900 results