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Page 1
Dominance of CD8 responses specific for epitopes bound by a single major histocompatibility complex class I molecule during the acute phase of viral infection.
Mothé BR, Horton H, Carter DK, Allen TM, Liebl ME, Skinner P, Vogel TU, Fuenger S, Vielhuber K, Rehrauer W, Wilson N, Franchini G, Altman JD, Haase A, Picker LJ, Allison DB, Watkins DI. Mothé BR, et al. Among authors: watkins di. J Virol. 2002 Jan;76(2):875-84. doi: 10.1128/jvi.76.2.875-884.2002. J Virol. 2002. PMID: 11752176 Free PMC article.
Immunization of rhesus macaques with a DNA prime/modified vaccinia virus Ankara boost regimen induces broad simian immunodeficiency virus (SIV)-specific T-cell responses and reduces initial viral replication but does not prevent disease progression following challenge with pathogenic SIVmac239.
Horton H, Vogel TU, Carter DK, Vielhuber K, Fuller DH, Shipley T, Fuller JT, Kunstman KJ, Sutter G, Montefiori DC, Erfle V, Desrosiers RC, Wilson N, Picker LJ, Wolinsky SM, Wang C, Allison DB, Watkins DI. Horton H, et al. Among authors: watkins di. J Virol. 2002 Jul;76(14):7187-202. doi: 10.1128/jvi.76.14.7187-7202.2002. J Virol. 2002. PMID: 12072518 Free PMC article. Clinical Trial.
Effects of cytotoxic T lymphocytes (CTL) directed against a single simian immunodeficiency virus (SIV) Gag CTL epitope on the course of SIVmac239 infection.
Allen TM, Jing P, Calore B, Horton H, O'Connor DH, Hanke T, Piekarczyk M, Ruddersdorf R, Mothé BR, Emerson C, Wilson N, Lifson JD, Belyakov IM, Berzofsky JA, Wang C, Allison DB, Montefiori DC, Desrosiers RC, Wolinsky S, Kunstman KJ, Altman JD, Sette A, McMichael AJ, Watkins DI. Allen TM, et al. Among authors: watkins di. J Virol. 2002 Oct;76(20):10507-11. doi: 10.1128/jvi.76.20.10507-10511.2002. J Virol. 2002. PMID: 12239328 Free PMC article.
Escape in one of two cytotoxic T-lymphocyte epitopes bound by a high-frequency major histocompatibility complex class I molecule, Mamu-A*02: a paradigm for virus evolution and persistence?
Vogel TU, Friedrich TC, O'Connor DH, Rehrauer W, Dodds EJ, Hickman H, Hildebrand W, Sidney J, Sette A, Hughes A, Horton H, Vielhuber K, Rudersdorf R, De Souza IP, Reynolds MR, Allen TM, Wilson N, Watkins DI. Vogel TU, et al. Among authors: watkins di. J Virol. 2002 Nov;76(22):11623-36. doi: 10.1128/jvi.76.22.11623-11636.2002. J Virol. 2002. PMID: 12388723 Free PMC article.
Multispecific vaccine-induced mucosal cytotoxic T lymphocytes reduce acute-phase viral replication but fail in long-term control of simian immunodeficiency virus SIVmac239.
Vogel TU, Reynolds MR, Fuller DH, Vielhuber K, Shipley T, Fuller JT, Kunstman KJ, Sutter G, Marthas ML, Erfle V, Wolinsky SM, Wang C, Allison DB, Rud EW, Wilson N, Montefiori D, Altman JD, Watkins DI. Vogel TU, et al. Among authors: watkins di. J Virol. 2003 Dec;77(24):13348-60. doi: 10.1128/jvi.77.24.13348-13360.2003. J Virol. 2003. PMID: 14645590 Free PMC article.
Extraepitopic compensatory substitutions partially restore fitness to simian immunodeficiency virus variants that escape from an immunodominant cytotoxic-T-lymphocyte response.
Friedrich TC, Frye CA, Yant LJ, O'Connor DH, Kriewaldt NA, Benson M, Vojnov L, Dodds EJ, Cullen C, Rudersdorf R, Hughes AL, Wilson N, Watkins DI. Friedrich TC, et al. Among authors: watkins di. J Virol. 2004 Mar;78(5):2581-5. doi: 10.1128/jvi.78.5.2581-2585.2004. J Virol. 2004. PMID: 14963161 Free PMC article.
Reversion of CTL escape-variant immunodeficiency viruses in vivo.
Friedrich TC, Dodds EJ, Yant LJ, Vojnov L, Rudersdorf R, Cullen C, Evans DT, Desrosiers RC, Mothé BR, Sidney J, Sette A, Kunstman K, Wolinsky S, Piatak M, Lifson J, Hughes AL, Wilson N, O'Connor DH, Watkins DI. Friedrich TC, et al. Among authors: watkins di. Nat Med. 2004 Mar;10(3):275-81. doi: 10.1038/nm998. Epub 2004 Feb 15. Nat Med. 2004. PMID: 14966520
Consequences of cytotoxic T-lymphocyte escape: common escape mutations in simian immunodeficiency virus are poorly recognized in naive hosts.
Friedrich TC, McDermott AB, Reynolds MR, Piaskowski S, Fuenger S, De Souza IP, Rudersdorf R, Cullen C, Yant LJ, Vojnov L, Stephany J, Martin S, O'Connor DH, Wilson N, Watkins DI. Friedrich TC, et al. Among authors: watkins di. J Virol. 2004 Sep;78(18):10064-73. doi: 10.1128/JVI.78.18.10064-10073.2004. J Virol. 2004. PMID: 15331739 Free PMC article.
265 results