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Nef promotes evasion of human immunodeficiency virus type 1-infected cells from the CTLA-4-mediated inhibition of T-cell activation.
El-Far M, Ancuta P, Routy JP, Zhang Y, Bakeman W, Bordi R, DaFonseca S, Said EA, Gosselin A, Tep TS, Eichbaum Q, van Grevenynghe J, Schwartz O, Freeman GJ, Haddad EK, Chomont N, Sékaly RP. El-Far M, et al. J Gen Virol. 2015 Jun;96(Pt 6):1463-1477. doi: 10.1099/vir.0.000065. Epub 2015 Jan 27. J Gen Virol. 2015. PMID: 25626682 Free PMC article.
CD160 and PD-1 co-expression on HIV-specific CD8 T cells defines a subset with advanced dysfunction.
Peretz Y, He Z, Shi Y, Yassine-Diab B, Goulet JP, Bordi R, Filali-Mouhim A, Loubert JB, El-Far M, Dupuy FP, Boulassel MR, Tremblay C, Routy JP, Bernard N, Balderas R, Haddad EK, Sékaly RP. Peretz Y, et al. PLoS Pathog. 2012;8(8):e1002840. doi: 10.1371/journal.ppat.1002840. Epub 2012 Aug 16. PLoS Pathog. 2012. PMID: 22916009 Free PMC article. Clinical Trial.
T-cell exhaustion in HIV infection.
El-Far M, Halwani R, Said E, Trautmann L, Doroudchi M, Janbazian L, Fonseca S, van Grevenynghe J, Yassine-Diab B, Sékaly RP, Haddad EK. El-Far M, et al. Curr HIV/AIDS Rep. 2008 Feb;5(1):13-9. doi: 10.1007/s11904-008-0003-7. Curr HIV/AIDS Rep. 2008. PMID: 18417030 Review.
Down-regulation of CTLA-4 by HIV-1 Nef protein.
El-Far M, Isabelle C, Chomont N, Bourbonnière M, Fonseca S, Ancuta P, Peretz Y, Chouikh Y, Halwani R, Schwartz O, Madrenas J, Freeman GJ, Routy JP, Haddad EK, Sékaly RP. El-Far M, et al. PLoS One. 2013;8(1):e54295. doi: 10.1371/journal.pone.0054295. Epub 2013 Jan 23. PLoS One. 2013. PMID: 23372701 Free PMC article.
122 results