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Cell and molecular determinants of in vivo efficacy of the BH3 mimetic ABT-263 against pediatric acute lymphoblastic leukemia xenografts.
Suryani S, Carol H, Chonghaile TN, Frismantas V, Sarmah C, High L, Bornhauser B, Cowley MJ, Szymanska B, Evans K, Boehm I, Tonna E, Jones L, Manesh DM, Kurmasheva RT, Billups C, Kaplan W, Letai A, Bourquin JP, Houghton PJ, Smith MA, Lock RB. Suryani S, et al. Among authors: kaplan w. Clin Cancer Res. 2014 Sep 1;20(17):4520-31. doi: 10.1158/1078-0432.CCR-14-0259. Epub 2014 Jul 10. Clin Cancer Res. 2014. PMID: 25013123 Free PMC article.
Consolidation of the cancer genome into domains of repressive chromatin by long-range epigenetic silencing (LRES) reduces transcriptional plasticity.
Coolen MW, Stirzaker C, Song JZ, Statham AL, Kassir Z, Moreno CS, Young AN, Varma V, Speed TP, Cowley M, Lacaze P, Kaplan W, Robinson MD, Clark SJ. Coolen MW, et al. Among authors: kaplan w. Nat Cell Biol. 2010 Mar;12(3):235-46. doi: 10.1038/ncb2023. Epub 2010 Feb 21. Nat Cell Biol. 2010. PMID: 20173741 Free PMC article.
Clonal expansions of cytotoxic T cells exist in the blood of patients with Waldenstrom macroglobulinemia but exhibit anergic properties and are eliminated by nucleoside analogue therapy.
Li J, Sze DM, Brown RD, Cowley MJ, Kaplan W, Mo SL, Yang S, Aklilu E, Kabani K, Loh YS, Yamagishi T, Chen Y, Ho PJ, Joshua DE. Li J, et al. Among authors: kaplan w. Blood. 2010 Apr 29;115(17):3580-8. doi: 10.1182/blood-2009-10-246991. Epub 2010 Feb 26. Blood. 2010. PMID: 20190191 Free article.
The antiproliferative effects of progestins in T47D breast cancer cells are tempered by progestin induction of the ETS transcription factor Elf5.
Hilton HN, Kalyuga M, Cowley MJ, Alles MC, Lee HJ, Caldon CE, Blazek K, Kaplan W, Musgrove EA, Daly RJ, Naylor MJ, Graham JD, Clarke CL, Ormandy CJ. Hilton HN, et al. Among authors: kaplan w. Mol Endocrinol. 2010 Jul;24(7):1380-92. doi: 10.1210/me.2009-0516. Epub 2010 Jun 2. Mol Endocrinol. 2010. PMID: 20519331 Free PMC article.
An early inflammatory gene profile in visceral adipose tissue in children.
Tam CS, Heilbronn LK, Henegar C, Wong M, Cowell CT, Cowley MJ, Kaplan W, Clément K, Baur LA. Tam CS, et al. Among authors: kaplan w. Int J Pediatr Obes. 2011 Jun;6(2-2):e360-3. doi: 10.3109/17477166.2011.575152. Epub 2011 May 24. Int J Pediatr Obes. 2011. PMID: 21609243 Free PMC article.
463 results