Verma VA - Search Results

1

Simplified Bryostatin Analogues Protect Cells from Chikungunya Virus-Induced Cell Death.

Staveness D, Abdelnabi R, Schrier AJ, Loy BA, Verma VA, DeChristopher BA, Near KE, Neyts J, Delang L, Leyssen P, Wender PA. Staveness D, et al. Among authors: verma va. J Nat Prod. 2016 Apr 22;79(4):675-9. doi: 10.1021/acs.jnatprod.5b01016. Epub 2016 Feb 22. J Nat Prod. 2016. PMID: 26900625 Free PMC article.

2

Design, synthesis, and biological evaluation of a potent, PKC selective, B-ring analog of bryostatin.

Wender PA, Verma VA. Wender PA, et al. Among authors: verma va. Org Lett. 2006 Apr 27;8(9):1893-6. doi: 10.1021/ol060457z. Org Lett. 2006. PMID: 16623578

3

The design, synthesis, and evaluation of C7 diversified bryostatin analogs reveals a hot spot for PKC affinity.

Wender PA, Verma VA. Wender PA, et al. Among authors: verma va. Org Lett. 2008 Aug 7;10(15):3331-4. doi: 10.1021/ol801235h. Epub 2008 Jun 28. Org Lett. 2008. PMID: 18588309 Free PMC article.

4

Total synthesis and initial biological evaluation of new B-ring-modified bryostatin analogs.

Wender PA, Horan JC, Verma VA. Wender PA, et al. Among authors: verma va. Org Lett. 2006 Nov 9;8(23):5299-302. doi: 10.1021/ol0620904. Org Lett. 2006. PMID: 17078702

5

Design, synthesis, and evaluation of potent bryostatin analogs that modulate PKC translocation selectivity.

Wender PA, Baryza JL, Brenner SE, DeChristopher BA, Loy BA, Schrier AJ, Verma VA. Wender PA, et al. Among authors: verma va. Proc Natl Acad Sci U S A. 2011 Apr 26;108(17):6721-6. doi: 10.1073/pnas.1015270108. Epub 2011 Mar 17. Proc Natl Acad Sci U S A. 2011. PMID: 21415363 Free PMC article.

6

Function-oriented synthesis, step economy, and drug design.

Wender PA, Verma VA, Paxton TJ, Pillow TH. Wender PA, et al. Among authors: verma va. Acc Chem Res. 2008 Jan;41(1):40-9. doi: 10.1021/ar700155p. Epub 2007 Dec 27. Acc Chem Res. 2008. PMID: 18159936 Review.

7

A cellular model of Alzheimer's disease therapeutic efficacy: PKC activation reverses Abeta-induced biomarker abnormality on cultured fibroblasts.

Khan TK, Nelson TJ, Verma VA, Wender PA, Alkon DL. Khan TK, et al. Among authors: verma va. Neurobiol Dis. 2009 May;34(2):332-9. doi: 10.1016/j.nbd.2009.02.003. Epub 2009 Feb 20. Neurobiol Dis. 2009. PMID: 19233276 Free PMC article.

8

Actin is the primary cellular receptor of bistramide A.

Statsuk AV, Bai R, Baryza JL, Verma VA, Hamel E, Wender PA, Kozmin SA. Statsuk AV, et al. Among authors: verma va. Nat Chem Biol. 2005 Dec;1(7):383-8. doi: 10.1038/nchembio748. Nat Chem Biol. 2005. PMID: 16372404

9

The cryptophycins as potent payloads for antibody drug conjugates.

Verma VA, Pillow TH, DePalatis L, Li G, Phillips GL, Polson AG, Raab HE, Spencer S, Zheng B. Verma VA, et al. Bioorg Med Chem Lett. 2015 Feb 15;25(4):864-8. doi: 10.1016/j.bmcl.2014.12.070. Epub 2015 Jan 2. Bioorg Med Chem Lett. 2015. PMID: 25613677

10

Exploration of Pyrrolobenzodiazepine (PBD)-Dimers Containing Disulfide-Based Prodrugs as Payloads for Antibody-Drug Conjugates.

Pei Z, Chen C, Chen J, Cruz-Chuh JD, Delarosa R, Deng Y, Fourie-O'Donohue A, Figueroa I, Guo J, Jin W, Khojasteh SC, Kozak KR, Latifi B, Lee J, Li G, Lin E, Liu L, Lu J, Martin S, Ng C, Nguyen T, Ohri R, Lewis Phillips G, Pillow TH, Rowntree RK, Stagg NJ, Stokoe D, Ulufatu S, Verma VA, Wai J, Wang J, Xu K, Xu Z, Yao H, Yu SF, Zhang D, Dragovich PS. Pei Z, et al. Among authors: verma va. Mol Pharm. 2018 Sep 4;15(9):3979-3996. doi: 10.1021/acs.molpharmaceut.8b00431. Epub 2018 Aug 6. Mol Pharm. 2018. PMID: 30040421

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