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Radical surgery versus organ preservation via short-course radiotherapy followed by transanal endoscopic microsurgery for early-stage rectal cancer (TREC): a randomised, open-label feasibility study.
Bach SP, Gilbert A, Brock K, Korsgen S, Geh I, Hill J, Gill T, Hainsworth P, Tutton MG, Khan J, Robinson J, Steward M, Cunningham C, Levy B, Beveridge A, Handley K, Kaur M, Marchevsky N, Magill L, Russell A, Quirke P, West NP, Sebag-Montefiore D; TREC collaborators. Bach SP, et al. Lancet Gastroenterol Hepatol. 2021 Feb;6(2):92-105. doi: 10.1016/S2468-1253(20)30333-2. Epub 2020 Dec 11. Lancet Gastroenterol Hepatol. 2021. PMID: 33308452 Free PMC article. Clinical Trial.
Canonical Wnt signals combined with suppressed TGFβ/BMP pathways promote renewal of the native human colonic epithelium.
Reynolds A, Wharton N, Parris A, Mitchell E, Sobolewski A, Kam C, Bigwood L, El Hadi A, Münsterberg A, Lewis M, Speakman C, Stebbings W, Wharton R, Sargen K, Tighe R, Jamieson C, Hernon J, Kapur S, Oue N, Yasui W, Williams MR. Reynolds A, et al. Among authors: speakman c. Gut. 2014 Apr;63(4):610-21. doi: 10.1136/gutjnl-2012-304067. Epub 2013 Jul 5. Gut. 2014. PMID: 23831735 Free PMC article.
The colon-selective spasmolytic otilonium bromide inhibits muscarinic M(3) receptor-coupled calcium signals in isolated human colonic crypts.
Lindqvist S, Hernon J, Sharp P, Johns N, Addison S, Watson M, Tighe R, Greer S, Mackay J, Rhodes M, Lewis M, Stebbings W, Speakman C, Evangelista S, Johnson I, Williams M. Lindqvist S, et al. Among authors: speakman c. Br J Pharmacol. 2002 Dec;137(7):1134-42. doi: 10.1038/sj.bjp.0704942. Br J Pharmacol. 2002. PMID: 12429587 Free PMC article.
Prophylactic biological mesh reinforcement versus standard closure of stoma site (ROCSS): a multicentre, randomised controlled trial.
Reinforcement of Closure of Stoma Site (ROCSS) Collaborative and West Midlands Research Collaborative. Reinforcement of Closure of Stoma Site (ROCSS) Collaborative and West Midlands Research Collaborative. Lancet. 2020 Feb 8;395(10222):417-426. doi: 10.1016/S0140-6736(19)32637-6. Lancet. 2020. PMID: 32035551 Free PMC article. Clinical Trial.
63 results