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Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses.
Sheahan TP, Sims AC, Graham RL, Menachery VD, Gralinski LE, Case JB, Leist SR, Pyrc K, Feng JY, Trantcheva I, Bannister R, Park Y, Babusis D, Clarke MO, Mackman RL, Spahn JE, Palmiotti CA, Siegel D, Ray AS, Cihlar T, Jordan R, Denison MR, Baric RS. Sheahan TP, et al. Among authors: menachery vd. Sci Transl Med. 2017 Jun 28;9(396):eaal3653. doi: 10.1126/scitranslmed.aal3653. Sci Transl Med. 2017. PMID: 28659436 Free PMC article.
Severe Acute Respiratory Syndrome Coronavirus 2 from Patient with Coronavirus Disease, United States.
Harcourt J, Tamin A, Lu X, Kamili S, Sakthivel SK, Murray J, Queen K, Tao Y, Paden CR, Zhang J, Li Y, Uehara A, Wang H, Goldsmith C, Bullock HA, Wang L, Whitaker B, Lynch B, Gautam R, Schindewolf C, Lokugamage KG, Scharton D, Plante JA, Mirchandani D, Widen SG, Narayanan K, Makino S, Ksiazek TG, Plante KS, Weaver SC, Lindstrom S, Tong S, Menachery VD, Thornburg NJ. Harcourt J, et al. Among authors: menachery vd. Emerg Infect Dis. 2020 Jun;26(6):1266-1273. doi: 10.3201/eid2606.200516. Epub 2020 Jun 17. Emerg Infect Dis. 2020. PMID: 32160149 Free PMC article.
An Infectious cDNA Clone of SARS-CoV-2.
Xie X, Muruato A, Lokugamage KG, Narayanan K, Zhang X, Zou J, Liu J, Schindewolf C, Bopp NE, Aguilar PV, Plante KS, Weaver SC, Makino S, LeDuc JW, Menachery VD, Shi PY. Xie X, et al. Among authors: menachery vd. Cell Host Microbe. 2020 May 13;27(5):841-848.e3. doi: 10.1016/j.chom.2020.04.004. Epub 2020 Apr 13. Cell Host Microbe. 2020. PMID: 32289263 Free PMC article.
The search for a COVID-19 animal model.
Lakdawala SS, Menachery VD. Lakdawala SS, et al. Among authors: menachery vd. Science. 2020 May 29;368(6494):942-943. doi: 10.1126/science.abc6141. Science. 2020. PMID: 32467379 No abstract available.
Isolation and characterization of SARS-CoV-2 from the first US COVID-19 patient.
Harcourt J, Tamin A, Lu X, Kamili S, Sakthivel SK, Murray J, Queen K, Tao Y, Paden CR, Zhang J, Li Y, Uehara A, Wang H, Goldsmith C, Bullock HA, Wang L, Whitaker B, Lynch B, Gautam R, Schindewolf C, Lokugamage KG, Scharton D, Plante JA, Mirchandani D, Widen SG, Narayanan K, Makino S, Ksiazek TG, Plante KS, Weaver SC, Lindstrom S, Tong S, Menachery VD, Thornburg NJ. Harcourt J, et al. Among authors: menachery vd. bioRxiv [Preprint]. 2020 Mar 7:2020.03.02.972935. doi: 10.1101/2020.03.02.972935. bioRxiv. 2020. PMID: 32511316 Free PMC article. Preprint.
Topoisomerase III-ß is required for efficient replication of positive-sense RNA viruses.
Prasanth KR, Hirano M, Fagg WS, McAnarney ET, Shan C, Xie X, Hage A, Pietzsch CA, Bukreyev A, Rajsbaum R, Shi PY, Bedford MT, Bradrick SS, Menachery V, Garcia-Blanco MA. Prasanth KR, et al. bioRxiv [Preprint]. 2020 Mar 27:2020.03.24.005900. doi: 10.1101/2020.03.24.005900. bioRxiv. 2020. PMID: 32511318 Free PMC article. Updated. Preprint.
Type I interferon susceptibility distinguishes SARS-CoV-2 from SARS-CoV.
Lokugamage KG, Hage A, de Vries M, Valero-Jimenez AM, Schindewolf C, Dittmann M, Rajsbaum R, Menachery VD. Lokugamage KG, et al. Among authors: menachery vd. bioRxiv [Preprint]. 2020 Jul 13:2020.03.07.982264. doi: 10.1101/2020.03.07.982264. bioRxiv. 2020. PMID: 32511335 Free PMC article. Updated. Preprint.
143 results