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Anti-type I interferon antibodies as a cause of severe COVID-19.
Fajgenbaum DC, Hayday AC, Rogers AJ, Towers GJ, Wack A, Zanoni I. Fajgenbaum DC, et al. Among authors: wack a. Fac Rev. 2022 Jun 10;11:15. doi: 10.12703/r-01-0000010. eCollection 2022. Fac Rev. 2022. PMID: 35812362 Free PMC article.
COVID-19 and emerging viral infections: The case for interferon lambda.
Prokunina-Olsson L, Alphonse N, Dickenson RE, Durbin JE, Glenn JS, Hartmann R, Kotenko SV, Lazear HM, O'Brien TR, Odendall C, Onabajo OO, Piontkivska H, Santer DM, Reich NC, Wack A, Zanoni I. Prokunina-Olsson L, et al. Among authors: wack a. J Exp Med. 2020 May 4;217(5):e20200653. doi: 10.1084/jem.20200653. J Exp Med. 2020. PMID: 32289152 Free PMC article.
Severity of SARS-CoV-2 infection as a function of the interferon landscape across the respiratory tract of COVID-19 patients.
Sposito B, Broggi A, Pandolfi L, Crotta S, Ferrarese R, Sisti S, Clementi N, Ambrosi A, Liu E, Frangipane V, Saracino L, Marongiu L, Facchini FA, Bottazzi A, Fossali T, Colombo R, Clementi M, Tagliabue E, Pontiroli AE, Meloni F, Wack A, Mancini N, Zanoni I. Sposito B, et al. Among authors: wack a. bioRxiv [Preprint]. 2021 Mar 30:2021.03.30.437173. doi: 10.1101/2021.03.30.437173. bioRxiv. 2021. PMID: 33821280 Free PMC article. Updated. Preprint.
The interferon landscape along the respiratory tract impacts the severity of COVID-19.
Sposito B, Broggi A, Pandolfi L, Crotta S, Clementi N, Ferrarese R, Sisti S, Criscuolo E, Spreafico R, Long JM, Ambrosi A, Liu E, Frangipane V, Saracino L, Bozzini S, Marongiu L, Facchini FA, Bottazzi A, Fossali T, Colombo R, Clementi M, Tagliabue E, Chou J, Pontiroli AE, Meloni F, Wack A, Mancini N, Zanoni I. Sposito B, et al. Among authors: wack a. Cell. 2021 Sep 16;184(19):4953-4968.e16. doi: 10.1016/j.cell.2021.08.016. Epub 2021 Aug 19. Cell. 2021. PMID: 34492226 Free PMC article.
A family of conserved bacterial virulence factors dampens interferon responses by blocking calcium signaling.
Alphonse N, Wanford JJ, Voak AA, Gay J, Venkhaya S, Burroughs O, Mathew S, Lee T, Evans SL, Zhao W, Frowde K, Alrehaili A, Dickenson RE, Munk M, Panina S, Mahmood IF, Llorian M, Stanifer ML, Boulant S, Berchtold MW, Bergeron JRC, Wack A, Lesser CF, Odendall C. Alphonse N, et al. Among authors: wack a. Cell. 2022 Jun 23;185(13):2354-2369.e17. doi: 10.1016/j.cell.2022.04.028. Epub 2022 May 13. Cell. 2022. PMID: 35568036 Free PMC article.
Impaired immune response drives age-dependent severity of COVID-19.
Beer J, Crotta S, Breithaupt A, Ohnemus A, Becker J, Sachs B, Kern L, Llorian M, Ebert N, Labroussaa F, Nhu Thao TT, Trueeb BS, Jores J, Thiel V, Beer M, Fuchs J, Kochs G, Wack A, Schwemmle M, Schnepf D. Beer J, et al. Among authors: wack a. J Exp Med. 2022 Dec 5;219(12):e20220621. doi: 10.1084/jem.20220621. Epub 2022 Sep 21. J Exp Med. 2022. PMID: 36129445 Free PMC article.
Interfering with transmission.
Wack A. Wack A. Elife. 2018 May 24;7:e37552. doi: 10.7554/eLife.37552. Elife. 2018. PMID: 29792400 Free PMC article.
An ace model for SARS-CoV-2 infection.
Major J, Wack A. Major J, et al. Among authors: wack a. J Exp Med. 2020 Dec 7;217(12):e20201748. doi: 10.1084/jem.20201748. J Exp Med. 2020. PMID: 33000129 Free PMC article.
122 results