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Choroid plexus-targeted NKCC1 overexpression to treat post-hemorrhagic hydrocephalus.
Sadegh C, Xu H, Sutin J, Fatou B, Gupta S, Pragana A, Taylor M, Kalugin PN, Zawadzki ME, Alturkistani O, Shipley FB, Dani N, Fame RM, Wurie Z, Talati P, Schleicher RL, Klein EM, Zhang Y, Holtzman MJ, Moore CI, Lin PY, Patel AB, Warf BC, Kimberly WT, Steen H, Andermann ML, Lehtinen MK. Sadegh C, et al. Among authors: holtzman mj. Neuron. 2023 May 17;111(10):1591-1608.e4. doi: 10.1016/j.neuron.2023.02.020. Epub 2023 Mar 8. Neuron. 2023. PMID: 36893755 Free PMC article.
A potent MAPK13-14 inhibitor prevents airway inflammation and mucus production.
Keeler SP, Wu K, Zhang Y, Mao D, Li M, Iberg CA, Austin SR, Glaser SA, Yantis J, Podgorny S, Brody SL, Chartock JR, Han Z, Byers DE, Romero AG, Holtzman MJ. Keeler SP, et al. Among authors: holtzman mj. Am J Physiol Lung Cell Mol Physiol. 2023 Dec 1;325(6):L726-L740. doi: 10.1152/ajplung.00183.2023. Epub 2023 Oct 17. Am J Physiol Lung Cell Mol Physiol. 2023. PMID: 37847710
IL-33 potentiates histaminergic itch.
Trier AM, Ver Heul AM, Fredman A, Le V, Wang Z, Auyeung K, Meixiong J, Lovato P, Holtzman MJ, Wang F, Dong X, Ji AL, Kim BS. Trier AM, et al. Among authors: holtzman mj. J Allergy Clin Immunol. 2024 Mar;153(3):852-859.e3. doi: 10.1016/j.jaci.2023.08.038. Epub 2023 Nov 18. J Allergy Clin Immunol. 2024. PMID: 37984799 Free article.
Defining diurnal fluctuations in mouse choroid plexus and CSF at high molecular, spatial, and temporal resolution.
Fame RM, Kalugin PN, Petrova B, Xu H, Soden PA, Shipley FB, Dani N, Grant B, Pragana A, Head JP, Gupta S, Shannon ML, Chifamba FF, Hawks-Mayer H, Vernon A, Gao F, Zhang Y, Holtzman MJ, Heiman M, Andermann ML, Kanarek N, Lipton JO, Lehtinen MK. Fame RM, et al. Among authors: holtzman mj. Nat Commun. 2023 Jun 22;14(1):3720. doi: 10.1038/s41467-023-39326-3. Nat Commun. 2023. PMID: 37349305 Free PMC article.
233 results