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A potent MAPK13-14 inhibitor prevents airway inflammation and mucus production.
Keeler SP, Wu K, Zhang Y, Mao D, Li M, Iberg CA, Austin SR, Glaser SA, Yantis J, Podgorny S, Brody SL, Chartock JR, Han Z, Byers DE, Romero AG, Holtzman MJ. Keeler SP, et al. Am J Physiol Lung Cell Mol Physiol. 2023 Dec 1;325(6):L726-L740. doi: 10.1152/ajplung.00183.2023. Epub 2023 Oct 17. Am J Physiol Lung Cell Mol Physiol. 2023. PMID: 37847710
A potent MAPK13-14 inhibitor prevents airway inflammation and mucus production.
Keeler SP, Wu K, Zhang Y, Mao D, Li M, Iberg CA, Austin SR, Glaser SA, Yantis J, Podgorny S, Brody SL, Chartock JR, Han Z, Byers DE, Romero AG, Holtzman MJ. Keeler SP, et al. bioRxiv [Preprint]. 2023 Oct 4:2023.05.26.542451. doi: 10.1101/2023.05.26.542451. bioRxiv. 2023. PMID: 37292761 Free PMC article. Updated. Preprint.
Chloride channel accessory 1 gene deficiency causes selective loss of mucus production in a new pig model.
Keeler SP, Yantis J, Gerovac BJ, Youkilis SL, Podgorny S, Mao D, Zhang Y, Whitworth KM, Redel B, Samuel MS, Wells KD, Prather RS, Holtzman MJ. Keeler SP, et al. Am J Physiol Lung Cell Mol Physiol. 2022 Jun 1;322(6):L842-L852. doi: 10.1152/ajplung.00443.2021. Epub 2022 Apr 19. Am J Physiol Lung Cell Mol Physiol. 2022. PMID: 35438004 Free PMC article.
Age-Dependent Reduction in Asthmatic Pathology through Reprogramming of Postviral Inflammatory Responses.
Hazan G, Eubanks A, Gierasch C, Atkinson J, Fox C, Hernandez-Leyva A, Rosen AL, Kau AL, Agapov E, Alexander-Brett J, Steinberg D, Kelley D, White M, Byers D, Wu K, Keeler SP, Zhang Y, Koenitzer JR, Eiden E, Anderson N, Holtzman MJ, Haspel J. Hazan G, et al. Among authors: keeler sp. J Immunol. 2022 Mar 15;208(6):1467-1482. doi: 10.4049/jimmunol.2101094. Epub 2022 Feb 16. J Immunol. 2022. PMID: 35173037 Free PMC article.
Basal epithelial stem cells cross an alarmin checkpoint for postviral lung disease.
Wu K, Kamimoto K, Zhang Y, Yang K, Keeler SP, Gerovac BJ, Agapov EV, Austin SP, Yantis J, Gissy KA, Byers DE, Alexander-Brett J, Hoffmann CM, Wallace M, Hughes ME, Crouch EC, Morris SA, Holtzman MJ. Wu K, et al. Among authors: keeler sp. J Clin Invest. 2021 Oct 1;131(19):e149336. doi: 10.1172/JCI149336. J Clin Invest. 2021. PMID: 34343135 Free PMC article.
37 results